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HUMAN:LPAR6
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | LPAR6 (synonyms: P2RY5) | |
| Protein Name(s) | Lysophosphatidic acid receptor 6
LPA receptor 6 LPA-6 Oleoyl-L-alpha-lysophosphatidic acid receptor P2Y purinoceptor 5 P2Y5 Purinergic receptor 5 RB intron encoded G-protein coupled receptor | |
| External Links | ||
| UniProt | P43657 | |
| EMBL | L11910 L78805 AF000546 BX537392 BX537438 BX537445 AK122856 AK223389 HQ995530 JF810890 AF551763 AL392048 CH471075 BC040850 BC045651 BC070295 BC106756 | |
| CCDS | CCDS9410.1 | |
| PIR | T09508 | |
| RefSeq | NP_001155969.1 NP_001155970.1 NP_005758.2 | |
| UniGene | Hs.123464 | |
| ProteinModelPortal | P43657 | |
| SMR | P43657 | |
| BioGrid | 115463 | |
| IntAct | P43657 | |
| BindingDB | P43657 | |
| ChEMBL | CHEMBL2331058 | |
| GuidetoPHARMACOLOGY | 163 | |
| PhosphoSite | P43657 | |
| DMDM | 34223726 | |
| PaxDb | P43657 | |
| PRIDE | P43657 | |
| DNASU | 10161 | |
| Ensembl | ENST00000345941 ENST00000378434 ENST00000620633 | |
| GeneID | 10161 | |
| KEGG | hsa:10161 | |
| UCSC | uc001vce.3 | |
| CTD | 10161 | |
| GeneCards | GC13M048963 | |
| HGNC | HGNC:15520 | |
| HPA | HPA028934 | |
| MIM | 278150 609239 | |
| neXtProt | NX_P43657 | |
| Orphanet | 55654 170 | |
| PharmGKB | PA165505129 | |
| eggNOG | NOG289230 | |
| GeneTree | ENSGT00760000118784 | |
| HOVERGEN | HBG101917 | |
| InParanoid | P43657 | |
| KO | K04273 | |
| OMA | FRIFYFA | |
| OrthoDB | EOG71VSSZ | |
| PhylomeDB | P43657 | |
| TreeFam | TF350009 | |
| Reactome | REACT_18283 REACT_18289 | |
| GenomeRNAi | 10161 | |
| NextBio | 38470 | |
| PRO | PR:P43657 | |
| Proteomes | UP000005640 | |
| Bgee | P43657 | |
| ExpressionAtlas | P43657 | |
| Genevestigator | P43657 | |
| GO | GO:0016021 GO:0005886 GO:0004930 | |
| InterPro | IPR000276 IPR017452 | |
| Pfam | PF00001 | |
| PRINTS | PR00237 | |
| PROSITE | PS00237 PS50262 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051482 |
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000660850 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035025 |
positive regulation of Rho protein signal transduction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101802 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1929509 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101802 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001835 |
blastocyst hatching |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8BMC0 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
Reactome:R-HSA-388396 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-749452 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Pasternack, SM et al. (2008) G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth. Nat. Genet. 40 329-34 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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