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HUMAN:LIPH
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | LIPH (synonyms: LPDLR, MPAPLA1, PLA1B) | |
| Protein Name(s) | Lipase member H
LIPH LPD lipase-related protein Membrane-associated phosphatidic acid-selective phospholipase A1-alpha mPA-PLA1 alpha Phospholipase A1 member B | |
| External Links | ||
| UniProt | Q8WWY8 | |
| EMBL | AY036912 AY093498 EF186229 AK074229 AK122651 CH471052 BC064941 | |
| CCDS | CCDS3272.1 | |
| RefSeq | NP_640341.1 | |
| UniGene | Hs.68864 | |
| ProteinModelPortal | Q8WWY8 | |
| SMR | Q8WWY8 | |
| BioGrid | 128352 | |
| STRING | 9606.ENSP00000296252 | |
| PhosphoSite | Q8WWY8 | |
| DMDM | 74762634 | |
| PaxDb | Q8WWY8 | |
| PRIDE | Q8WWY8 | |
| DNASU | 200879 | |
| Ensembl | ENST00000296252 | |
| GeneID | 200879 | |
| KEGG | hsa:200879 | |
| UCSC | uc003fpm.3 | |
| CTD | 200879 | |
| GeneCards | GC03M185224 | |
| HGNC | HGNC:18483 | |
| HPA | HPA049079 | |
| MIM | 604379 607365 | |
| neXtProt | NX_Q8WWY8 | |
| Orphanet | 55654 170 | |
| PharmGKB | PA134934352 | |
| eggNOG | NOG39787 | |
| GeneTree | ENSGT00760000119069 | |
| HOGENOM | HOG000234386 | |
| HOVERGEN | HBG080640 | |
| InParanoid | Q8WWY8 | |
| OMA | ITAYPCD | |
| OrthoDB | EOG79PJP2 | |
| PhylomeDB | Q8WWY8 | |
| TreeFam | TF324997 | |
| BRENDA | 3.1.1.32 | |
| ChiTaRS | LIPH | |
| GeneWiki | LIPH | |
| GenomeRNAi | 200879 | |
| NextBio | 89990 | |
| PRO | PR:Q8WWY8 | |
| Proteomes | UP000005640 | |
| Bgee | Q8WWY8 | |
| CleanEx | HS_LIPH | |
| ExpressionAtlas | Q8WWY8 | |
| Genevestigator | Q8WWY8 | |
| GO | GO:0005615 GO:0005886 GO:0008201 GO:0004620 GO:0016042 | |
| Gene3D | 3.40.50.1820 | |
| InterPro | IPR029058 IPR016272 IPR013818 IPR000734 | |
| PANTHER | PTHR11610 | |
| Pfam | PF00151 | |
| PIRSF | PIRSF000865 | |
| PRINTS | PR00821 | |
| SUPFAM | SSF53474 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016787 |
hydrolase activity |
ECO:0000314 |
F |
This paper discusses the effects and functions of Lipase member H and provides necessary information for the annotation. |
complete | |||||
|
involved_in |
GO:0016042 |
lipid catabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008201 |
heparin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004620 |
phospholipase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0052689 |
carboxylic ester hydrolase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006654 |
phosphatidic acid biosynthetic process |
Reactome:R-HSA-1483166 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-6792445 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016042 |
lipid catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008201 |
heparin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cui, M et al. (2014) Lipase member H is a novel secreted protein associated with a poor prognosis for breast cancer patients. Tumour Biol. 35 11461-5 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Hiramatsu, T et al. (2003) Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta. J. Biol. Chem. 278 49438-47 PubMed GONUTS page
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