GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:LIPG

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) LIPF
Protein Name(s) Gastric triacylglycerol lipase

GL Gastric lipase

External Links
UniProt P07098
EMBL X05997
X05997
AK301310
AK301320
AK312940
AL833751
AY631869
AL358532
CH471066
BC112272
BC113711
CCDS CCDS55718.1
CCDS55719.1
CCDS65896.1
CCDS7389.1
PIR S07145
RefSeq NP_001185757.1
NP_001185758.1
NP_001185759.1
NP_004181.1
UniGene Hs.523130
PDB 1HLG
PDBsum 1HLG
ProteinModelPortal P07098
SMR P07098
BioGrid 114085
IntAct P07098
STRING 9606.ENSP00000238983
ChEMBL CHEMBL1796
DrugBank DB01083
PhosphoSite P07098
DMDM 126306
PaxDb P07098
PRIDE P07098
DNASU 8513
Ensembl ENST00000238983
ENST00000355843
ENST00000394375
ENST00000608620
GeneID 8513
KEGG hsa:8513
UCSC uc001kfg.2
uc010qmu.2
CTD 8513
GeneCards GC10P090415
HGNC HGNC:6622
HPA HPA045930
MIM 601980
neXtProt NX_P07098
PharmGKB PA30394
eggNOG COG0596
GeneTree ENSGT00550000074328
HOGENOM HOG000240694
HOVERGEN HBG006265
InParanoid P07098
KO K14452
OMA WARRNLY
OrthoDB EOG71RXJN
PhylomeDB P07098
TreeFam TF315485
ChiTaRS LIPF
EvolutionaryTrace P07098
GenomeRNAi 8513
NextBio 31864
PMAP-CutDB P07098
PRO PR:P07098
Proteomes UP000005640
Bgee P07098
CleanEx HS_LIPF
Genevestigator P07098
GO GO:0005576
GO:0005739
GO:0008289
GO:0016615
GO:0004806
GO:0016042
GO:0006108
GO:0006641
Gene3D 3.40.50.1820
InterPro IPR029058
IPR000073
IPR006693
IPR025483
Pfam PF04083
PF00561
PIRSF PIRSF000862
SUPFAM SSF53474
PROSITE PS00120

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004806

triglyceride lipase activity

PMID:10411623[1]

ECO:0000314

F

Table 3

complete

enables

GO:0008289

lipid binding

PMID:2753032[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006641

triglyceride metabolic process

PMID:3304425[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005575

cellular_component

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0044255

cellular lipid metabolic process

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002591693
SGD:S000001623

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000109216
UniProtKB:P38571

C

Seeded From UniProt

complete

enables

GO:0016298

lipase activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002591693
RGD:3008
TAIR:locus:2174648
UniProtKB:P38571

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016615

P

Seeded From UniProt

complete

enables

GO:0016615

malate dehydrogenase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P04634
ensembl:ENSRNOP00000027969

F

Seeded From UniProt

complete

involved_in

GO:0006108

malate metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P04634
ensembl:ENSRNOP00000027969

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P04634
ensembl:ENSRNOP00000027969

C

Seeded From UniProt

complete

enables

GO:0004806

triglyceride lipase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039097

F

Seeded From UniProt

complete

enables

GO:0016788

hydrolase activity, acting on ester bonds

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR025483

F

Seeded From UniProt

complete

enables

GO:0004806

triglyceride lipase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.3

F

Seeded From UniProt

complete

enables

GO:0004806

triglyceride lipase activity

PMID:3304425[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

involved_in

GO:0016042

lipid catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0442

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Wicker-Planquart, C et al. (1999) Site-directed removal of N-glycosylation sites in human gastric lipase. Eur. J. Biochem. 262 644-51 PubMed GONUTS page
  2. Bernbäck, S & Bläckberg, L (1989) Human gastric lipase. The N-terminal tetrapeptide is essential for lipid binding and lipase activity. Eur. J. Biochem. 182 495-9 PubMed GONUTS page
  3. 3.0 3.1 Bodmer, MW et al. (1987) Molecular cloning of a human gastric lipase and expression of the enzyme in yeast. Biochim. Biophys. Acta 909 237-44 PubMed GONUTS page
  4. 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page