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HUMAN:LIPG
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | LIPF | |
Protein Name(s) | Gastric triacylglycerol lipase
GL Gastric lipase | |
External Links | ||
UniProt | P07098 | |
EMBL | X05997 X05997 AK301310 AK301320 AK312940 AL833751 AY631869 AL358532 CH471066 BC112272 BC113711 | |
CCDS | CCDS55718.1 CCDS55719.1 CCDS65896.1 CCDS7389.1 | |
PIR | S07145 | |
RefSeq | NP_001185757.1 NP_001185758.1 NP_001185759.1 NP_004181.1 | |
UniGene | Hs.523130 | |
PDB | 1HLG | |
PDBsum | 1HLG | |
ProteinModelPortal | P07098 | |
SMR | P07098 | |
BioGrid | 114085 | |
IntAct | P07098 | |
STRING | 9606.ENSP00000238983 | |
ChEMBL | CHEMBL1796 | |
DrugBank | DB01083 | |
PhosphoSite | P07098 | |
DMDM | 126306 | |
PaxDb | P07098 | |
PRIDE | P07098 | |
DNASU | 8513 | |
Ensembl | ENST00000238983 ENST00000355843 ENST00000394375 ENST00000608620 | |
GeneID | 8513 | |
KEGG | hsa:8513 | |
UCSC | uc001kfg.2 uc010qmu.2 | |
CTD | 8513 | |
GeneCards | GC10P090415 | |
HGNC | HGNC:6622 | |
HPA | HPA045930 | |
MIM | 601980 | |
neXtProt | NX_P07098 | |
PharmGKB | PA30394 | |
eggNOG | COG0596 | |
GeneTree | ENSGT00550000074328 | |
HOGENOM | HOG000240694 | |
HOVERGEN | HBG006265 | |
InParanoid | P07098 | |
KO | K14452 | |
OMA | WARRNLY | |
OrthoDB | EOG71RXJN | |
PhylomeDB | P07098 | |
TreeFam | TF315485 | |
ChiTaRS | LIPF | |
EvolutionaryTrace | P07098 | |
GenomeRNAi | 8513 | |
NextBio | 31864 | |
PMAP-CutDB | P07098 | |
PRO | PR:P07098 | |
Proteomes | UP000005640 | |
Bgee | P07098 | |
CleanEx | HS_LIPF | |
Genevestigator | P07098 | |
GO | GO:0005576 GO:0005739 GO:0008289 GO:0016615 GO:0004806 GO:0016042 GO:0006108 GO:0006641 | |
Gene3D | 3.40.50.1820 | |
InterPro | IPR029058 IPR000073 IPR006693 IPR025483 | |
Pfam | PF04083 PF00561 | |
PIRSF | PIRSF000862 | |
SUPFAM | SSF53474 | |
PROSITE | PS00120 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0004806 |
triglyceride lipase activity |
ECO:0000314 |
F |
Table 3 |
complete | |||||
enables |
GO:0008289 |
lipid binding |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006641 |
triglyceride metabolic process |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005575 |
cellular_component |
ECO:0000307 |
no biological data found used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0044255 |
cellular lipid metabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002591693 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000109216 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0016298 |
lipase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002591693 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0016615 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0016615 |
malate dehydrogenase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P04634 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006108 |
malate metabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P04634 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P04634 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004806 |
triglyceride lipase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016788 |
hydrolase activity, acting on ester bonds |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004806 |
triglyceride lipase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004806 |
triglyceride lipase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016042 |
lipid catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Wicker-Planquart, C et al. (1999) Site-directed removal of N-glycosylation sites in human gastric lipase. Eur. J. Biochem. 262 644-51 PubMed GONUTS page
- ↑ Bernbäck, S & Bläckberg, L (1989) Human gastric lipase. The N-terminal tetrapeptide is essential for lipid binding and lipase activity. Eur. J. Biochem. 182 495-9 PubMed GONUTS page
- ↑ 3.0 3.1 Bodmer, MW et al. (1987) Molecular cloning of a human gastric lipase and expression of the enzyme in yeast. Biochim. Biophys. Acta 909 237-44 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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