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HUMAN:KRT85

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) KRT85 (synonyms: KRTHB5)
Protein Name(s) Keratin, type II cuticular Hb5

Hair keratin K2.12 Keratin-85 K85 Type II hair keratin Hb5 Type-II keratin Kb25

External Links
UniProt P78386
EMBL X99140
Y19210
CCDS CCDS8824.1
RefSeq NP_001287739.1
NP_002274.1
UniGene Hs.182507
ProteinModelPortal P78386
SMR P78386
BioGrid 110089
IntAct P78386
STRING 9606.ENSP00000257901
PhosphoSite P78386
DMDM 48474780
MaxQB P78386
PaxDb P78386
PeptideAtlas P78386
PRIDE P78386
DNASU 3891
Ensembl ENST00000257901
GeneID 3891
KEGG hsa:3891
UCSC uc001sag.3
CTD 3891
GeneCards GC12M052753
HGNC HGNC:6462
MIM 602032
602767
neXtProt NX_P78386
Orphanet 69084
PharmGKB PA30251
eggNOG NOG150019
GeneTree ENSGT00760000118796
HOGENOM HOG000230976
HOVERGEN HBG013015
InParanoid P78386
KO K07605
OMA SCGPRMA
OrthoDB EOG7B05CW
PhylomeDB P78386
TreeFam TF332742
GeneWiki KRT85
GenomeRNAi 3891
NextBio 15277
PRO PR:P78386
Proteomes UP000005640
Bgee P78386
CleanEx HS_KRT85
ExpressionAtlas P78386
Genevestigator P78386
GO GO:0005615
GO:0045095
GO:0005198
GO:0008544
InterPro IPR001664
IPR018039
IPR003054
PANTHER PTHR23239
Pfam PF00038
PRINTS PR01276
PROSITE PS00226

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005615

extracellular space

PMID:23580065[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001827)

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001664

F

Seeded From UniProt

complete

part_of

GO:0005882

intermediate filament

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001664

C

Seeded From UniProt

complete

part_of

GO:0045095

keratin filament

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003054

C

Seeded From UniProt

complete

involved_in

GO:0008544

epidermis development

PMID:9084137[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

PMID:9084137[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0070268

cornification

Reactome:R-HSA-6809371

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031424

keratinization

Reactome:R-HSA-6805567

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-8942224
Reactome:R-HSA-6814764
Reactome:R-HSA-6814734
Reactome:R-HSA-6814387
Reactome:R-HSA-6814298
Reactome:R-HSA-6811539
Reactome:R-HSA-6810937
Reactome:R-HSA-6810357
Reactome:R-HSA-6809663
Reactome:R-HSA-6809393
Reactome:R-HSA-6806629
Reactome:R-HSA-6806613
Reactome:R-HSA-6806610
Reactome:R-HSA-6805573
Reactome:R-HSA-6805546

ECO:0000304

author statement supported by traceable reference used in manual assertion















C

Seeded From UniProt

complete

part_of

GO:0005882

intermediate filament

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0416
UniProtKB-KW:KW-0403

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Pieragostino, D et al. (2013) Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Mol Biosyst 9 1108-16 PubMed GONUTS page
  2. 2.0 2.1 Rogers, MA et al. (1997) Sequences and differential expression of three novel human type-II hair keratins. Differentiation 61 187-94 PubMed GONUTS page