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HUMAN:KRT84

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) KRT84 (synonyms: KRTHB4)
Protein Name(s) Keratin, type II cuticular Hb4

Keratin-84 K84 Type II hair keratin Hb4 Type-II keratin Kb24

External Links
UniProt Q9NSB2
EMBL Y19209
AK314030
AC078865
BC069647
AJ628420
CCDS CCDS8825.1
RefSeq NP_149034.2
UniGene Hs.272336
ProteinModelPortal Q9NSB2
SMR Q9NSB2
BioGrid 110088
IntAct Q9NSB2
STRING 9606.ENSP00000257951
PhosphoSite Q9NSB2
DMDM 311033397
MaxQB Q9NSB2
PaxDb Q9NSB2
PRIDE Q9NSB2
Ensembl ENST00000257951
GeneID 3890
KEGG hsa:3890
UCSC uc001sah.1
CTD 3890
GeneCards GC12M052771
HGNC HGNC:6461
MIM 602766
neXtProt NX_Q9NSB2
PharmGKB PA30250
eggNOG NOG149575
GeneTree ENSGT00760000118796
HOGENOM HOG000230976
HOVERGEN HBG013015
InParanoid Q9NSB2
KO K07605
OMA EEIRICE
OrthoDB EOG7FV3Q8
PhylomeDB Q9NSB2
TreeFam TF317854
GenomeRNAi 3890
NextBio 15273
PRO PR:Q9NSB2
Proteomes UP000005640
Bgee Q9NSB2
CleanEx HS_KRT84
Genevestigator Q9NSB2
GO GO:0070062
GO:0045095
GO:0005200
GO:0030280
GO:0001942
GO:0035878
GO:0045616
InterPro IPR001664
IPR018039
IPR003054
PANTHER PTHR23239
Pfam PF00038
PRINTS PR01276
PROSITE PS00226

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0070062

extracellular exosome

PMID:23533145[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0045095

keratin filament

PMID:10692104[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0035878

nail development

PMID:10692104[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005200

structural constituent of cytoskeleton

PMID:10692104[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0001942

hair follicle development

PMID:10692104[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007010

cytoskeleton organization

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005200

P

Seeded From UniProt

complete

involved_in

GO:0045616

regulation of keratinocyte differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99M73
ensembl:ENSMUSP00000023720

P

Seeded From UniProt

complete

part_of

GO:0045111

intermediate filament cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99M73
ensembl:ENSMUSP00000023720

C

Seeded From UniProt

complete

enables

GO:0030280

structural constituent of epidermis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99M73
ensembl:ENSMUSP00000023720

F

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001664

F

Seeded From UniProt

complete

part_of

GO:0005882

intermediate filament

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001664

C

Seeded From UniProt

complete

part_of

GO:0045095

keratin filament

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003054

C

Seeded From UniProt

complete

involved_in

GO:0070268

cornification

Reactome:R-HSA-6809371

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031424

keratinization

Reactome:R-HSA-6805567

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-8942224
Reactome:R-HSA-6814764
Reactome:R-HSA-6814734
Reactome:R-HSA-6814387
Reactome:R-HSA-6814298
Reactome:R-HSA-6811539
Reactome:R-HSA-6810937
Reactome:R-HSA-6810357
Reactome:R-HSA-6809663
Reactome:R-HSA-6809393
Reactome:R-HSA-6806629
Reactome:R-HSA-6806613
Reactome:R-HSA-6806610
Reactome:R-HSA-6805573
Reactome:R-HSA-6805546

ECO:0000304

author statement supported by traceable reference used in manual assertion















C

Seeded From UniProt

complete

part_of

GO:0005882

intermediate filament

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0403
UniProtKB-KW:KW-0416

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Rogers, MA et al. (2000) Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain. J. Invest. Dermatol. 114 464-72 PubMed GONUTS page