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HUMAN:KPCD3
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | PRKD3 (synonyms: EPK2, PRKCN) | |
| Protein Name(s) | Serine/threonine-protein kinase D3
Protein kinase C nu type Protein kinase EPK2 nPKC-nu | |
| External Links | ||
| UniProt | O94806 | |
| EMBL | AB015982 AC007390 CH471053 CH471053 BC030706 | |
| CCDS | CCDS1789.1 | |
| RefSeq | NP_005804.1 XP_005264294.1 | |
| UniGene | Hs.660757 Hs.716034 | |
| PDB | 2D9Z | |
| PDBsum | 2D9Z | |
| ProteinModelPortal | O94806 | |
| SMR | O94806 | |
| BioGrid | 117199 | |
| IntAct | O94806 | |
| MINT | MINT-5003932 | |
| STRING | 9606.ENSP00000234179 | |
| BindingDB | O94806 | |
| ChEMBL | CHEMBL2595 | |
| GuidetoPHARMACOLOGY | 2174 | |
| PhosphoSite | O94806 | |
| MaxQB | O94806 | |
| PaxDb | O94806 | |
| PRIDE | O94806 | |
| DNASU | 23683 | |
| Ensembl | ENST00000234179 ENST00000379066 | |
| GeneID | 23683 | |
| KEGG | hsa:23683 | |
| UCSC | uc002rqd.3 uc002rqf.1 | |
| CTD | 23683 | |
| GeneCards | GC02M037477 | |
| H-InvDB | HIX0030377 | |
| HGNC | HGNC:9408 | |
| HPA | HPA029529 | |
| MIM | 607077 | |
| neXtProt | NX_O94806 | |
| PharmGKB | PA33772 | |
| eggNOG | COG0515 | |
| GeneTree | ENSGT00770000120480 | |
| HOGENOM | HOG000015135 | |
| HOVERGEN | HBG003564 | |
| InParanoid | O94806 | |
| KO | K06070 | |
| OMA | HYTSRDT | |
| OrthoDB | EOG75B84N | |
| PhylomeDB | O94806 | |
| TreeFam | TF314320 | |
| BRENDA | 2.7.11.13 | |
| SignaLink | O94806 | |
| ChiTaRS | PRKD3 | |
| EvolutionaryTrace | O94806 | |
| GeneWiki | PRKD3 | |
| GenomeRNAi | 23683 | |
| NextBio | 46561 | |
| PRO | PR:O94806 | |
| Proteomes | UP000005640 | |
| Bgee | O94806 | |
| CleanEx | HS_PRKD3 | |
| ExpressionAtlas | O94806 | |
| Genevestigator | O94806 | |
| GO | GO:0005737 GO:0016020 GO:0005634 GO:0005524 GO:0046872 GO:0004697 GO:0035556 GO:0007205 GO:0006468 | |
| Gene3D | 2.30.29.30 | |
| InterPro | IPR020454 IPR011009 IPR002219 IPR001849 IPR011993 IPR000719 IPR017441 IPR015727 IPR002290 IPR008271 | |
| PANTHER | PTHR22968 | |
| Pfam | PF00130 PF00169 PF00069 | |
| PIRSF | PIRSF000552 | |
| PRINTS | PR00008 | |
| SMART | SM00109 SM00233 SM00220 | |
| SUPFAM | SSF56112 | |
| PROSITE | PS50003 PS00107 PS50011 PS00108 PS00479 PS50081 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016301 |
kinase activity |
ECO:0000314 |
F |
Figure 1 |
complete | |||||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0089700 |
protein kinase D signaling |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000540182 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004697 |
protein kinase C activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035556 |
intracellular signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004697 |
protein kinase C activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007205 |
protein kinase C-activating G protein-coupled receptor signaling pathway |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004697 |
protein kinase C activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030148 |
sphingolipid biosynthetic process |
Reactome:R-HSA-1660661 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-429698 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Pusapati, GV et al. (2012) Protein kinase D regulates RhoA activity via rhotekin phosphorylation. J. Biol. Chem. 287 9473-83 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Hayashi, A et al. (1999) PKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmu. Biochim. Biophys. Acta 1450 99-106 PubMed GONUTS page
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