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HUMAN:KISS1
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | KISS1 | |
Protein Name(s) | Metastasis-suppressor KiSS-1
Kisspeptin-1 Metastin Kisspeptin-54 Kisspeptin-14 Kisspeptin-13 Kisspeptin-10 | |
External Links | ||
UniProt | Q15726 | |
EMBL | U43527 AY117143 AF218017 AL592114 AK291695 BC022819 | |
CCDS | CCDS41454.1 | |
RefSeq | NP_002247.3 | |
UniGene | Hs.95008 | |
ProteinModelPortal | Q15726 | |
BioGrid | 110014 | |
STRING | 9606.ENSP00000356162 | |
PhosphoSite | Q15726 | |
PaxDb | Q15726 | |
PRIDE | Q15726 | |
DNASU | 3814 | |
Ensembl | ENST00000367194 | |
GeneID | 3814 | |
KEGG | hsa:3814 | |
UCSC | uc001har.3 | |
CTD | 3814 | |
GeneCards | GC01M204159 | |
GeneReviews | KISS1 | |
HGNC | HGNC:6341 | |
HPA | CAB017775 HPA035542 | |
MIM | 603286 614842 | |
neXtProt | NX_Q15726 | |
Orphanet | 432 | |
PharmGKB | PA30127 | |
eggNOG | NOG28509 | |
GeneTree | ENSGT00390000008827 | |
HOGENOM | HOG000013123 | |
HOVERGEN | HBG052261 | |
InParanoid | Q15726 | |
OMA | FLCATHF | |
OrthoDB | EOG79GT8B | |
PhylomeDB | Q15726 | |
TreeFam | TF338233 | |
Reactome | REACT_14819 REACT_18283 | |
ChiTaRS | KISS1 | |
GeneWiki | Kisspeptin | |
GenomeRNAi | 3814 | |
NextBio | 14991 | |
PMAP-CutDB | Q15726 | |
PRO | PR:Q15726 | |
Proteomes | UP000005640 | |
Bgee | Q15726 | |
CleanEx | HS_KISS1 | |
Genevestigator | Q15726 | |
GO | GO:0005576 GO:0007010 | |
InterPro | IPR020207 | |
Pfam | PF15152 | |
ProDom | PD088121 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0043005 |
neuron projection |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002704209 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0031773 |
kisspeptin receptor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002704209 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002704209 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2663985 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060124 |
positive regulation of growth hormone secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060112 |
generation of ovulation cycle rhythm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051482 |
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050806 |
positive regulation of synaptic transmission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043410 |
positive regulation of MAPK cascade |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0033686 |
positive regulation of luteinizing hormone secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0031773 |
kisspeptin receptor binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0016324 |
apical plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008285 |
negative regulation of cell population proliferation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007010 |
cytoskeleton organization |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
Reactome:R-HSA-388396 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005576 |
extracellular region |
Reactome:R-HSA-749452 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Lee, JH & Welch, DR (1997) Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1. Cancer Res. 57 2384-7 PubMed GONUTS page
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- GO:0033686 ! positive regulation of luteinizing hormone secretion
- GO:0043410 ! positive regulation of MAPK cascade
- GO:0050806 ! positive regulation of synaptic transmission
- GO:0060124 ! positive regulation of growth hormone secretion
- GO:0007204 ! positive regulation of cytosolic calcium ion concentration
- Primates