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HUMAN:KISS1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | KISS1 | |
| Protein Name(s) | Metastasis-suppressor KiSS-1
Kisspeptin-1 Metastin Kisspeptin-54 Kisspeptin-14 Kisspeptin-13 Kisspeptin-10 | |
| External Links | ||
| UniProt | Q15726 | |
| EMBL | U43527 AY117143 AF218017 AL592114 AK291695 BC022819 | |
| CCDS | CCDS41454.1 | |
| RefSeq | NP_002247.3 | |
| UniGene | Hs.95008 | |
| ProteinModelPortal | Q15726 | |
| BioGrid | 110014 | |
| STRING | 9606.ENSP00000356162 | |
| PhosphoSite | Q15726 | |
| PaxDb | Q15726 | |
| PRIDE | Q15726 | |
| DNASU | 3814 | |
| Ensembl | ENST00000367194 | |
| GeneID | 3814 | |
| KEGG | hsa:3814 | |
| UCSC | uc001har.3 | |
| CTD | 3814 | |
| GeneCards | GC01M204159 | |
| GeneReviews | KISS1 | |
| HGNC | HGNC:6341 | |
| HPA | CAB017775 HPA035542 | |
| MIM | 603286 614842 | |
| neXtProt | NX_Q15726 | |
| Orphanet | 432 | |
| PharmGKB | PA30127 | |
| eggNOG | NOG28509 | |
| GeneTree | ENSGT00390000008827 | |
| HOGENOM | HOG000013123 | |
| HOVERGEN | HBG052261 | |
| InParanoid | Q15726 | |
| OMA | FLCATHF | |
| OrthoDB | EOG79GT8B | |
| PhylomeDB | Q15726 | |
| TreeFam | TF338233 | |
| Reactome | REACT_14819 REACT_18283 | |
| ChiTaRS | KISS1 | |
| GeneWiki | Kisspeptin | |
| GenomeRNAi | 3814 | |
| NextBio | 14991 | |
| PMAP-CutDB | Q15726 | |
| PRO | PR:Q15726 | |
| Proteomes | UP000005640 | |
| Bgee | Q15726 | |
| CleanEx | HS_KISS1 | |
| Genevestigator | Q15726 | |
| GO | GO:0005576 GO:0007010 | |
| InterPro | IPR020207 | |
| Pfam | PF15152 | |
| ProDom | PD088121 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0043005 |
neuron projection |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002704209 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0031773 |
kisspeptin receptor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002704209 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002704209 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2663985 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060124 |
positive regulation of growth hormone secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060112 |
generation of ovulation cycle rhythm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051482 |
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0050806 |
positive regulation of synaptic transmission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043410 |
positive regulation of MAPK cascade |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043005 |
neuron projection |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0033686 |
positive regulation of luteinizing hormone secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0031773 |
kisspeptin receptor binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016324 |
apical plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008285 |
negative regulation of cell population proliferation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q7TSB7 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007010 |
cytoskeleton organization |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
Reactome:R-HSA-388396 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
Reactome:R-HSA-749452 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Lee, JH & Welch, DR (1997) Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1. Cancer Res. 57 2384-7 PubMed GONUTS page
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- GO:0033686 ! positive regulation of luteinizing hormone secretion
- GO:0043410 ! positive regulation of MAPK cascade
- GO:0050806 ! positive regulation of synaptic transmission
- GO:0060124 ! positive regulation of growth hormone secretion
- GO:0007204 ! positive regulation of cytosolic calcium ion concentration
- Primates