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HUMAN:KERA

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) KERA (synonyms: SLRR2B)
Protein Name(s) Keratocan

KTN Keratan sulfate proteoglycan keratocan

External Links
UniProt O60938
EMBL AF065988
AF063301
AF205403
BC032667
CCDS CCDS9037.1
RefSeq NP_008966.1
UniGene Hs.125750
ProteinModelPortal O60938
SMR O60938
BioGrid 116264
IntAct O60938
MINT MINT-7970761
STRING 9606.ENSP00000266719
PhosphoSite O60938
PaxDb O60938
PRIDE O60938
DNASU 11081
Ensembl ENST00000266719
GeneID 11081
KEGG hsa:11081
UCSC uc001tbl.3
CTD 11081
GeneCards GC12M091377
HGNC HGNC:6309
HPA HPA039321
MIM 217300
603288
neXtProt NX_O60938
Orphanet 53691
PharmGKB PA30088
eggNOG COG4886
GeneTree ENSGT00760000118969
HOGENOM HOG000234447
HOVERGEN HBG108061
InParanoid O60938
KO K08123
OMA MWVLFIT
OrthoDB EOG741Z2B
PhylomeDB O60938
TreeFam TF334562
Reactome REACT_121120
REACT_121313
REACT_267635
REACT_267713
GeneWiki Keratocan
GenomeRNAi 11081
NextBio 42130
PRO PR:O60938
Proteomes UP000005640
Bgee O60938
CleanEx HS_KERA
Genevestigator O60938
GO GO:0005576
GO:0005796
GO:0043202
GO:0005578
GO:0005975
GO:0061303
GO:0030203
GO:0018146
GO:0042340
GO:0042339
GO:0050896
GO:0044281
GO:0007601
InterPro IPR001611
IPR000372
Pfam PF13855
PF01462
SMART SM00013
PROSITE PS51450

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0031012

extracellular matrix

PMID:10802664[1]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0061303

cornea development in camera-type eye

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:O35367
ensembl:ENSMUSP00000100923

P

Seeded From UniProt

complete

part_of

GO:0043202

lysosomal lumen

Reactome:R-HSA-2046239
Reactome:R-HSA-1793217

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0042340

keratan sulfate catabolic process

Reactome:R-HSA-2022857

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0018146

keratan sulfate biosynthetic process

Reactome:R-HSA-2022854

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005796

Golgi lumen

Reactome:R-HSA-9035950
Reactome:R-HSA-9035949
Reactome:R-HSA-3656269
Reactome:R-HSA-3656258
Reactome:R-HSA-3656230
Reactome:R-HSA-2046298
Reactome:R-HSA-2046285
Reactome:R-HSA-2046265
Reactome:R-HSA-2046222
Reactome:R-HSA-2046180
Reactome:R-HSA-2046175
Reactome:R-HSA-2025724
Reactome:R-HSA-2025723

ECO:0000304

author statement supported by traceable reference used in manual assertion













C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

Reactome:R-HSA-2046239
Reactome:R-HSA-2046180

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0050896

response to stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0716

P

Seeded From UniProt

complete

involved_in

GO:0007601

visual perception

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0844

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Pellegata, NS et al. (2000) Mutations in KERA, encoding keratocan, cause cornea plana. Nat. Genet. 25 91-5 PubMed GONUTS page