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HUMAN:KCRS
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | CKMT2 | |
| Protein Name(s) | Creatine kinase S-type, mitochondrial
Basic-type mitochondrial creatine kinase Mib-CK Sarcomeric mitochondrial creatine kinase S-MtCK | |
| External Links | ||
| UniProt | P17540 | |
| EMBL | J05401 CR450315 BC029140 | |
| CCDS | CCDS4053.1 | |
| PIR | A35756 | |
| RefSeq | NP_001093205.1 NP_001093206.1 NP_001816.2 | |
| UniGene | Hs.80691 | |
| PDB | 2GL6 | |
| PDBsum | 2GL6 | |
| ProteinModelPortal | P17540 | |
| SMR | P17540 | |
| BioGrid | 107580 | |
| IntAct | P17540 | |
| MINT | MINT-5004086 | |
| STRING | 9606.ENSP00000254035 | |
| DrugBank | DB00148 | |
| PhosphoSite | P17540 | |
| DMDM | 116242603 | |
| UCD-2DPAGE | P17540 | |
| MaxQB | P17540 | |
| PaxDb | P17540 | |
| PRIDE | P17540 | |
| DNASU | 1160 | |
| Ensembl | ENST00000254035 ENST00000424301 ENST00000437669 | |
| GeneID | 1160 | |
| KEGG | hsa:1160 | |
| UCSC | uc003khc.4 | |
| CTD | 1160 | |
| GeneCards | GC05P080530 | |
| HGNC | HGNC:1996 | |
| HPA | HPA051880 | |
| MIM | 123295 | |
| neXtProt | NX_P17540 | |
| PharmGKB | PA26534 | |
| eggNOG | COG3869 | |
| GeneTree | ENSGT00550000074561 | |
| HOGENOM | HOG000232165 | |
| HOVERGEN | HBG001339 | |
| InParanoid | P17540 | |
| KO | K00933 | |
| OMA | MTSIESK | |
| OrthoDB | EOG7XM2XW | |
| PhylomeDB | P17540 | |
| TreeFam | TF314214 | |
| BioCyc | MetaCyc:HS05555-MONOMER | |
| Reactome | REACT_813 | |
| EvolutionaryTrace | P17540 | |
| GeneWiki | CKMT2 | |
| GenomeRNAi | 1160 | |
| NextBio | 4814 | |
| PRO | PR:P17540 | |
| Proteomes | UP000005640 | |
| Bgee | P17540 | |
| CleanEx | HS_CKMT2 | |
| ExpressionAtlas | P17540 | |
| Genevestigator | P17540 | |
| GO | GO:0005743 GO:0005739 GO:0005524 GO:0004111 GO:0034641 GO:0006600 GO:0006936 GO:0044281 | |
| Gene3D | 1.10.135.10 3.30.590.10 | |
| InterPro | IPR000749 IPR022415 IPR022414 IPR022413 IPR014746 | |
| PANTHER | PTHR11547 | |
| Pfam | PF00217 PF02807 | |
| SUPFAM | SSF48034 | |
| PROSITE | PS00112 PS51510 PS51509 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001134) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0046314 |
phosphocreatine biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88413 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88407 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:99441 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004111 |
creatine kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88407 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR022413 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000749 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004111 |
creatine kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006936 |
muscle contraction |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004111 |
creatine kinase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006600 |
creatine metabolic process |
Reactome:R-HSA-71288 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
Reactome:R-HSA-200326 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Zhao, X et al. (2011) Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes. Mol. Cell Proteomics 10 M110.000299 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Haas, RC & Strauss, AW (1990) Separate nuclear genes encode sarcomere-specific and ubiquitous human mitochondrial creatine kinase isoenzymes. J. Biol. Chem. 265 6921-7 PubMed GONUTS page
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