GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:KCNKI

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) KCNK18 (synonyms: TRESK, TRIK)
Protein Name(s) Potassium channel subfamily K member 18

TWIK-related individual potassium channel TWIK-related spinal cord potassium channel

External Links
UniProt Q7Z418
EMBL AB087138
AL731557
CCDS CCDS7598.1
RefSeq NP_862823.1
UniGene Hs.449650
ProteinModelPortal Q7Z418
SMR Q7Z418
BioGrid 130759
STRING 9606.ENSP00000334650
ChEMBL CHEMBL2331042
GuidetoPHARMACOLOGY 527
PhosphoSite Q7Z418
DMDM 74750072
PaxDb Q7Z418
PRIDE Q7Z418
DNASU 338567
Ensembl ENST00000334549
GeneID 338567
KEGG hsa:338567
UCSC uc010qsr.2
CTD 338567
GeneCards GC10P118947
HGNC HGNC:19439
HPA HPA044739
MIM 613655
613656
neXtProt NX_Q7Z418
PharmGKB PA134985465
eggNOG NOG311880
GeneTree ENSGT00700000104522
HOGENOM HOG000074045
HOVERGEN HBG104673
InParanoid Q7Z418
OMA AFKLVQN
OrthoDB EOG7MPRDX
PhylomeDB Q7Z418
TreeFam TF316115
Reactome REACT_75801
GeneWiki KCNK18
GenomeRNAi 338567
NextBio 97036
PRO PR:Q7Z418
Proteomes UP000005640
CleanEx HS_KCNK18
Genevestigator Q7Z418
GO GO:0005887
GO:0005886
GO:0015269
GO:0015271
GO:0005267
GO:0071467
GO:0071435
GO:0006813
GO:0007268
InterPro IPR003280
IPR013099
Pfam PF07885
PRINTS PR01333

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071467

cellular response to pH

PMID:12754259[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0097623

potassium ion export across plasma membrane

PMID:12754259[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015271

outward rectifier potassium channel activity

PMID:12754259[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:12754259[1]

ECO:0000305

curator inference used in manual assertion

GO:0015271

C

Seeded From UniProt

complete

involved_in

GO:0006813

potassium ion transport

PMID:20006580[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:20006580[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0017561
FB:FBgn0037690
FB:FBgn0038165
MGI:MGI:109322
PANTHER:PTN000108561
RGD:621447
RGD:621448
RGD:621449
TAIR:locus:2117681
UniProtKB:O00180
UniProtKB:Q8LIN5
UniProtKB:Q9NYG8

P

Seeded From UniProt

complete

involved_in

GO:0030322

stabilization of membrane potential

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000108561
ZFIN:ZDB-GENE-100405-2

P

Seeded From UniProt

complete

enables

GO:0022841

potassium ion leak channel activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0017561
PANTHER:PTN000108561
RGD:621447
RGD:621448
UniProtKB:O00180
UniProtKB:O14649

F

Seeded From UniProt

complete

enables

GO:0015271

outward rectifier potassium channel activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000108684
UniProtKB:Q7Z418

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109322
PANTHER:PTN000108561
RGD:621447
RGD:621448
RGD:621449
UniProtKB:O00180
UniProtKB:Q9NYG8
WB:WBGene00006318

C

Seeded From UniProt

complete

enables

GO:0015269

calcium-activated potassium channel activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6VV64
ensembl:ENSMUSP00000065713

F

Seeded From UniProt

complete

involved_in

GO:0006813

potassium ion transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6VV64
ensembl:ENSMUSP00000065713

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6VV64
ensembl:ENSMUSP00000065713

C

Seeded From UniProt

complete

enables

GO:0005267

potassium channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003280

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003280

C

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003280

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-HSA-1299338

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0631

P

Seeded From UniProt

complete

involved_in

GO:0006813

potassium ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0633

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

enables

GO:0005267

potassium channel activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0631

F

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 Sano, Y et al. (2003) A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord. J. Biol. Chem. 278 27406-12 PubMed GONUTS page
  2. ↑ 2.0 2.1 Egenberger, B et al. (2010) N-linked glycosylation determines cell surface expression of two-pore-domain K+ channel TRESK. Biochem. Biophys. Res. Commun. 391 1262-7 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=HUMAN:KCNKI&oldid=5955926"