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HUMAN:K2C75
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | KRT75 (synonyms: K6HF, KB18) | |
Protein Name(s) | Keratin, type II cytoskeletal 75
Cytokeratin-75 CK-75 Keratin-6 hair follicle hK6hf Keratin-75 K75 Type II keratin-K6hf Type-II keratin Kb18 | |
External Links | ||
UniProt | O95678 | |
EMBL | Y17282 Y19212 AK298960 AC055736 | |
CCDS | CCDS8827.1 | |
RefSeq | NP_004684.2 | |
UniGene | Hs.697046 | |
ProteinModelPortal | O95678 | |
SMR | O95678 | |
BioGrid | 114567 | |
IntAct | O95678 | |
Allergome | 415 | |
PhosphoSite | O95678 | |
MaxQB | O95678 | |
PaxDb | O95678 | |
PeptideAtlas | O95678 | |
PRIDE | O95678 | |
DNASU | 9119 | |
Ensembl | ENST00000252245 | |
GeneID | 9119 | |
KEGG | hsa:9119 | |
UCSC | uc001saj.2 | |
CTD | 9119 | |
GeneCards | GC12M052817 | |
H-InvDB | HIX0036863 | |
HGNC | HGNC:24431 | |
HPA | HPA019367 | |
MIM | 600628 609025 612318 | |
neXtProt | NX_O95678 | |
PharmGKB | PA147357763 | |
eggNOG | NOG146769 | |
GeneTree | ENSGT00760000118796 | |
HOGENOM | HOG000230976 | |
HOVERGEN | HBG013015 | |
InParanoid | O95678 | |
KO | K07605 | |
OMA | RQSTITF | |
OrthoDB | EOG7FV3Q8 | |
PhylomeDB | O95678 | |
TreeFam | TF317854 | |
GenomeRNAi | 9119 | |
NextBio | 34175 | |
PRO | PR:O95678 | |
Proteomes | UP000005640 | |
Bgee | O95678 | |
CleanEx | HS_KRT75 | |
Genevestigator | O95678 | |
GO | GO:0070062 GO:0045095 GO:0005198 GO:0002244 | |
InterPro | IPR001664 IPR018039 IPR003054 | |
PANTHER | PTHR23239 | |
Pfam | PF00038 | |
PRINTS | PR01276 | |
PROSITE | PS00226 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0005882 |
intermediate filament |
ECO:0000314 |
C |
Fig. 4a, "Cells transfected with K6hfWT/K17...Note the fully extended IF network in a" |
complete | |||||
part_of |
GO:0005882 |
intermediate filament |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002244 |
hematopoietic progenitor cell differentiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8BGZ7 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005198 |
structural molecule activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005882 |
intermediate filament |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045095 |
keratin filament |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005198 |
structural molecule activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070268 |
cornification |
Reactome:R-HSA-6809371 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0031424 |
keratinization |
Reactome:R-HSA-6805567 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-8942224 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0005882 |
intermediate filament |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Winter, H et al. (2004) An unusual Ala12Thr polymorphism in the 1A alpha-helical segment of the companion layer-specific keratin K6hf: evidence for a risk factor in the etiology of the common hair disorder pseudofolliculitis barbae. J. Invest. Dermatol. 122 652-7 PubMed GONUTS page
- ↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
- ↑ Winter, H et al. (1998) A novel human type II cytokeratin, K6hf, specifically expressed in the companion layer of the hair follicle. J. Invest. Dermatol. 111 955-62 PubMed GONUTS page