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HUMAN:K2C6B

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) KRT6B (synonyms: K6B, KRTL1)
Protein Name(s) Keratin, type II cytoskeletal 6B

Cytokeratin-6B CK-6B Keratin-6B K6B Type-II keratin Kb10

External Links
UniProt P04259
EMBL L42592
L42584
L42585
L42586
L42587
L42588
L42589
L42590
L42612
L00205
M11229
L00198
L00199
L00200
L00201
L00202
L00203
L00204
AC055736
BC034535
CCDS CCDS8828.1
PIR I61767
I61771
RefSeq NP_005546.2
UniGene Hs.708950
ProteinModelPortal P04259
SMR P04259
BioGrid 110052
IntAct P04259
MINT MINT-1456452
STRING 9606.ENSP00000252252
Allergome 415
PhosphoSite P04259
DMDM 238054404
PaxDb P04259
PRIDE P04259
DNASU 3854
Ensembl ENST00000252252
GeneID 3854
KEGG hsa:3854
UCSC uc001sak.3
CTD 3854
GeneCards GC12M052840
GeneReviews KRT6B
HGNC HGNC:6444
HPA CAB000130
HPA045697
MIM 148042
615728
neXtProt NX_P04259
Orphanet 2309
PharmGKB PA30232
eggNOG NOG315845
GeneTree ENSGT00760000118796
HOGENOM HOG000230976
HOVERGEN HBG013015
InParanoid P04259
KO K07605
OMA FASFREC
OrthoDB EOG7FV3Q8
PhylomeDB P04259
TreeFam TF317854
GenomeRNAi 3854
NextBio 15165
PRO PR:P04259
Proteomes UP000005640
Bgee P04259
CleanEx HS_KRT6B
Genevestigator P04259
GO GO:0070062
GO:0045095
GO:0005200
GO:0007398
InterPro IPR001664
IPR018039
IPR003054
PANTHER PTHR23239
Pfam PF00038
PRINTS PR01276
PROSITE PS00226

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0070062

extracellular exosome

PMID:19199708[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001831)

Seeded From UniProt

complete

involved_in

GO:0007010

cytoskeleton organization

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005200

P

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001664

F

Seeded From UniProt

complete

part_of

GO:0005882

intermediate filament

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001664

C

Seeded From UniProt

complete

part_of

GO:0045095

keratin filament

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003054

C

Seeded From UniProt

complete

involved_in

GO:0007398

ectoderm development

PMID:9618173[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005200

structural constituent of cytoskeleton

PMID:9618173[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0070268

cornification

Reactome:R-HSA-6809371

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031424

keratinization

Reactome:R-HSA-6805567

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-8942224
Reactome:R-HSA-6814764
Reactome:R-HSA-6814734
Reactome:R-HSA-6814387
Reactome:R-HSA-6814298
Reactome:R-HSA-6811539
Reactome:R-HSA-6810937
Reactome:R-HSA-6810357
Reactome:R-HSA-6809663
Reactome:R-HSA-6809393
Reactome:R-HSA-6806629
Reactome:R-HSA-6806613
Reactome:R-HSA-6806610
Reactome:R-HSA-6805573
Reactome:R-HSA-6805546

ECO:0000304

author statement supported by traceable reference used in manual assertion















C

Seeded From UniProt

complete

part_of

GO:0005882

intermediate filament

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0403
UniProtKB-KW:KW-0416

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gonzalez-Begne, M et al. (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J. Proteome Res. 8 1304-14 PubMed GONUTS page
  2. 2.0 2.1 Smith, FJ et al. (1998) A mutation in human keratin K6b produces a phenocopy of the K17 disorder pachyonychia congenita type 2. Hum. Mol. Genet. 7 1143-8 PubMed GONUTS page