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HUMAN:K1C19
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | KRT19 | |
| Protein Name(s) | Keratin, type I cytoskeletal 19
Cytokeratin-19 CK-19 Keratin-19 K19 | |
| External Links | ||
| UniProt | P08727 | |
| EMBL | J03607 Y00503 AF202321 AK313261 AC019349 BC002539 BC007628 BC010409 BC067744 BC084574 AB045973 AB041267 | |
| CCDS | CCDS11399.1 | |
| PIR | A31370 | |
| RefSeq | NP_002267.2 | |
| UniGene | Hs.654568 | |
| ProteinModelPortal | P08727 | |
| SMR | P08727 | |
| BioGrid | 110078 | |
| DIP | DIP-35655N | |
| IntAct | P08727 | |
| MINT | MINT-1438883 | |
| PhosphoSite | P08727 | |
| DMDM | 311033484 | |
| SWISS-2DPAGE | P08727 | |
| MaxQB | P08727 | |
| PaxDb | P08727 | |
| PeptideAtlas | P08727 | |
| PRIDE | P08727 | |
| DNASU | 3880 | |
| Ensembl | ENST00000361566 | |
| GeneID | 3880 | |
| KEGG | hsa:3880 | |
| UCSC | uc002hxd.4 | |
| CTD | 3880 | |
| GeneCards | GC17M039679 | |
| HGNC | HGNC:6436 | |
| HPA | CAB000031 HPA002465 | |
| MIM | 148020 | |
| neXtProt | NX_P08727 | |
| PharmGKB | PA30225 | |
| eggNOG | NOG148784 | |
| GeneTree | ENSGT00760000118808 | |
| HOVERGEN | HBG013015 | |
| InParanoid | P08727 | |
| KO | K07604 | |
| OMA | GQEDHYN | |
| OrthoDB | EOG7FV3Q8 | |
| PhylomeDB | P08727 | |
| TreeFam | TF332742 | |
| ChiTaRS | KRT19 | |
| GeneWiki | Keratin_19 | |
| GenomeRNAi | 3880 | |
| NextBio | 15231 | |
| PRO | PR:P08727 | |
| Proteomes | UP000005640 | |
| Bgee | P08727 | |
| ExpressionAtlas | P08727 | |
| Genevestigator | P08727 | |
| GO | GO:0071944 GO:0043034 GO:0016010 GO:0070062 GO:0005882 GO:0042383 GO:0030018 GO:0005200 GO:0008307 GO:0060706 GO:0043627 GO:0045214 GO:0016032 | |
| InterPro | IPR001664 IPR018039 IPR002957 IPR009053 | |
| PANTHER | PTHR23239 | |
| Pfam | PF00038 | |
| PRINTS | PR01248 | |
| SUPFAM | SSF46579 | |
| PROSITE | PS00226 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005886 |
plasma membrane |
ECO:0000314 |
C |
Fig. 1D Through immunohistochemical staining, the CK-19 protein was found to be expressed in the plasma membrane. |
complete | |||||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001831) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045214 |
sarcomere organization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043627 |
response to estrogen |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043034 |
costamere |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008307 |
structural constituent of muscle |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0071944 |
cell periphery |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:1990357 |
terminal web |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19001 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060706 |
cell differentiation involved in embryonic placenta development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19001 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042383 |
sarcolemma |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19001 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030018 |
Z disc |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19001 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016327 |
apicolateral plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19001 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007219 |
Notch signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19001 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63279 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016010 |
dystrophin-associated glycoprotein complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63279 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005198 |
structural molecule activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005882 |
intermediate filament |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005882 |
intermediate filament |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005200 |
structural constituent of cytoskeleton |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070268 |
cornification |
Reactome:R-HSA-6809371 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031424 |
keratinization |
Reactome:R-HSA-6805567 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-8942224 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005882 |
intermediate filament |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Gkegkes, ID et al. (2013) Expression of caspase-14 and keratin-19 in the human epidermis and appendages during fetal skin development. Arch. Dermatol. Res. 305 379-87 PubMed GONUTS page
- ↑ Gonzalez-Begne, M et al. (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J. Proteome Res. 8 1304-14 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Stone, MR et al. (2005) Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19. Mol. Biol. Cell 16 4280-93 PubMed GONUTS page
- ↑ Yang, GP et al. (1999) Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes. Nucleic Acids Res. 27 1517-23 PubMed GONUTS page
- ↑ Hand, NJ et al. (2009) The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology 136 1081-90 PubMed GONUTS page
- ↑ 6.0 6.1 Eckert, RL (1988) Sequence of the human 40-kDa keratin reveals an unusual structure with very high sequence identity to the corresponding bovine keratin. Proc. Natl. Acad. Sci. U.S.A. 85 1114-8 PubMed GONUTS page
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