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HUMAN:ITA7
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ITGA7 | |
| Protein Name(s) | Integrin alpha-7
Integrin alpha-7 heavy chain Integrin alpha-7 light chain Integrin alpha-7 70 kDa form | |
| External Links | ||
| UniProt | Q13683 | |
| EMBL | AF032108 AF052050 AF072132 AJ228836 AJ228837 AJ228838 AJ228839 AJ228840 AJ228842 AJ228843 AJ228844 AJ228845 AJ228846 AJ228847 AJ228848 AJ228849 AJ228850 AJ228851 AJ228852 AJ228853 AJ228854 AJ228855 AJ228856 AJ228857 AJ228858 AJ228859 AJ228860 AJ228862 AJ228836 AJ228837 AJ228838 AJ228839 AJ228841 AJ228842 AJ228843 AJ228844 AJ228845 AJ228846 AJ228847 AJ228848 AJ228849 AJ228850 AJ228851 AJ228852 AJ228853 AJ228854 AJ228855 AJ228856 AJ228857 AJ228858 AJ228859 AJ228860 AJ228862 AY358882 AK304864 AC009779 BC050280 X74295 AF034833 | |
| CCDS | CCDS44914.1 CCDS55832.1 CCDS8888.1 | |
| PIR | JC5950 | |
| RefSeq | NP_001138468.1 NP_001138469.1 NP_002197.2 XP_005268896.1 XP_005268898.1 | |
| UniGene | Hs.524484 | |
| ProteinModelPortal | Q13683 | |
| SMR | Q13683 | |
| BioGrid | 109885 | |
| DIP | DIP-5981N | |
| IntAct | Q13683 | |
| MINT | MINT-140160 | |
| STRING | 9606.ENSP00000257879 | |
| PhosphoSite | Q13683 | |
| DMDM | 308153592 | |
| MaxQB | Q13683 | |
| PaxDb | Q13683 | |
| PRIDE | Q13683 | |
| Ensembl | ENST00000257879 ENST00000452168 ENST00000553804 ENST00000555728 | |
| GeneID | 3679 | |
| KEGG | hsa:3679 | |
| UCSC | uc001shg.3 uc001shh.3 uc010sps.2 | |
| CTD | 3679 | |
| GeneCards | GC12M056078 | |
| GeneReviews | ITGA7 | |
| H-InvDB | HIX0010702 HIX0201958 | |
| HGNC | HGNC:6143 | |
| HPA | HPA008427 | |
| MIM | 600536 613204 | |
| neXtProt | NX_Q13683 | |
| Orphanet | 2020 34520 | |
| PharmGKB | PA29943 | |
| eggNOG | NOG26407 | |
| GeneTree | ENSGT00760000118782 | |
| HOVERGEN | HBG108011 | |
| InParanoid | Q13683 | |
| KO | K06583 | |
| OMA | QGPGQKG | |
| PhylomeDB | Q13683 | |
| TreeFam | TF105391 | |
| Reactome | REACT_13552 REACT_163906 REACT_169262 | |
| SignaLink | Q13683 | |
| ChiTaRS | ITGA7 | |
| GeneWiki | ITGA7 | |
| GenomeRNAi | 3679 | |
| NextBio | 14399 | |
| PRO | PR:Q13683 | |
| Proteomes | UP000005640 | |
| Bgee | Q13683 | |
| CleanEx | HS_ITGA7 | |
| ExpressionAtlas | Q13683 | |
| Genevestigator | Q13683 | |
| GO | GO:0009986 GO:0005737 GO:0034677 GO:0005927 GO:0031594 GO:0005886 GO:0042383 GO:0046872 GO:0048514 GO:0016477 GO:0007160 GO:0035987 GO:0030198 GO:0034113 GO:0007229 GO:0007517 GO:0008360 GO:0007519 | |
| InterPro | IPR013517 IPR013519 IPR000413 IPR013649 IPR018184 | |
| Pfam | PF01839 PF08441 | |
| PRINTS | PR01185 | |
| SMART | SM00191 | |
| PROSITE | PS51470 PS00242 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0009986 |
cell surface |
ECO:0000305 |
curator inference used in manual assertion |
GO:0034113 |
C |
part_of:(CL:0002540) |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0034113 |
heterotypic cell-cell adhesion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035987 |
endodermal cell differentiation |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007155 |
cell adhesion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0008305 |
integrin complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007517 |
muscle organ development |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007160 |
cell-matrix adhesion |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030198 |
extracellular matrix organization |
Reactome:R-HSA-1474244 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-NUL-3907289 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0007229 |
integrin-mediated signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008360 |
regulation of cell shape |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007155 |
cell adhesion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Semon, JA et al. (2010) Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels. Cell Tissue Res. 341 147-58 PubMed GONUTS page
- ↑ Brafman, DA et al. (2013) Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Cell Death Differ. 20 369-81 PubMed GONUTS page
- ↑ Hayashi, YK et al. (1998) Mutations in the integrin alpha7 gene cause congenital myopathy. Nat. Genet. 19 94-7 PubMed GONUTS page
- ↑ 4.0 4.1 Mayer, U et al. (1997) Absence of integrin alpha 7 causes a novel form of muscular dystrophy. Nat. Genet. 17 318-23 PubMed GONUTS page
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