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HUMAN:INP4B

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) INPP4B
Protein Name(s) Type II inositol 3,4-bisphosphate 4-phosphatase

Inositol polyphosphate 4-phosphatase type II

External Links
UniProt O15327
EMBL U96922
AY753912
AC093860
AC093885
AC108060
AC108077
AC138657
AC139720
CH471056
BC017924
BC072447
BC110918
BC133005
CCDS CCDS3757.1
RefSeq NP_001095139.1
NP_003857.2
XP_006714465.1
UniGene Hs.531403
ProteinModelPortal O15327
SMR O15327
BioGrid 114348
STRING 9606.ENSP00000262992
DEPOD O15327
PhosphoSite O15327
MaxQB O15327
PaxDb O15327
PRIDE O15327
Ensembl ENST00000262992
ENST00000506217
ENST00000508116
ENST00000513000
GeneID 8821
KEGG hsa:8821
UCSC uc003iiw.4
CTD 8821
GeneCards GC04M142949
H-InvDB HIX0024592
HGNC HGNC:6075
HPA HPA037681
HPA037682
MIM 607494
neXtProt NX_O15327
PharmGKB PA29883
eggNOG NOG289097
GeneTree ENSGT00390000002033
HOGENOM HOG000113075
HOVERGEN HBG081796
InParanoid O15327
KO K01109
OrthoDB EOG7M3HZP
PhylomeDB O15327
TreeFam TF325637
BioCyc MetaCyc:HS03227-MONOMER
Reactome REACT_120756
REACT_121025
REACT_150352
UniPathway UPA00944
ChiTaRS INPP4B
GeneWiki INPP4B
GenomeRNAi 8821
NextBio 33090
PRO PR:O15327
Proteomes UP000005640
Bgee O15327
CleanEx HS_INPP4B
ExpressionAtlas O15327
Genevestigator O15327
GO GO:0005829
GO:0005794
GO:0008289
GO:0034594
GO:0016316
GO:0034597
GO:0006874
GO:0043647
GO:0045671
GO:0006661
GO:0036092
GO:0006644
GO:0046850
GO:0046822
GO:0051896
GO:0007165
GO:0044281
Gene3D 2.60.40.150
InterPro IPR000008
SUPFAM SSF49562

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0016316

phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000257020
RGD:620470

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2158925
PANTHER:PTN000257020

C

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0034597

P

Seeded From UniProt

complete

involved_in

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016316

P

Seeded From UniProt

complete

involved_in

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0016316

P

Seeded From UniProt

complete

involved_in

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0016316

P

Seeded From UniProt

complete

involved_in

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016316

P

Seeded From UniProt

complete

enables

GO:0016316

phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039034

F

Seeded From UniProt

complete

enables

GO:0016316

phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.3.66

F

Seeded From UniProt

complete

enables

GO:0034597

phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.3.66

F

Seeded From UniProt

complete

enables

GO:0016316

phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity

PMID:9295334[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

PMID:9295334[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043647

inositol phosphate metabolic process

Reactome:R-HSA-1855183

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006661

phosphatidylinositol biosynthetic process

Reactome:R-HSA-1660516
Reactome:R-HSA-1660499

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-1855202
Reactome:R-HSA-1855180
Reactome:R-HSA-1676164
Reactome:R-HSA-1676162

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 Norris, FA et al. (1997) The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family. J. Biol. Chem. 272 23859-64 PubMed GONUTS page