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HUMAN:IGBP1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | IGBP1 (synonyms: IBP1) | |
| Protein Name(s) | Immunoglobulin-binding protein 1
B-cell signal transduction molecule alpha 4 Protein alpha-4 CD79a-binding protein 1 Protein phosphatase 2/4/6 regulatory subunit Renal carcinoma antigen NY-REN-16 | |
| External Links | ||
| UniProt | P78318 | |
| EMBL | Y08915 BT006736 AL158141 AL139111 BC004137 | |
| CCDS | CCDS14396.1 | |
| RefSeq | NP_001542.1 | |
| UniGene | Hs.496267 | |
| PDB | 4IYP | |
| PDBsum | 4IYP | |
| ProteinModelPortal | P78318 | |
| SMR | P78318 | |
| BioGrid | 109698 | |
| IntAct | P78318 | |
| MINT | MINT-3022988 | |
| STRING | 9606.ENSP00000348784 | |
| PhosphoSite | P78318 | |
| DMDM | 14285501 | |
| MaxQB | P78318 | |
| PaxDb | P78318 | |
| PeptideAtlas | P78318 | |
| PRIDE | P78318 | |
| DNASU | 3476 | |
| Ensembl | ENST00000342206 ENST00000356413 | |
| GeneID | 3476 | |
| KEGG | hsa:3476 | |
| UCSC | uc004dxv.3 | |
| CTD | 3476 | |
| GeneCards | GC0XP069353 | |
| HGNC | HGNC:5461 | |
| HPA | CAB034139 HPA000634 HPA001004 | |
| MIM | 300139 300472 | |
| neXtProt | NX_P78318 | |
| Orphanet | 52055 | |
| PharmGKB | PA29694 | |
| eggNOG | NOG332001 | |
| GeneTree | ENSGT00390000002414 | |
| HOGENOM | HOG000038526 | |
| HOVERGEN | HBG052090 | |
| InParanoid | P78318 | |
| KO | K17606 | |
| OMA | GSRIIQD | |
| OrthoDB | EOG7992R2 | |
| PhylomeDB | P78318 | |
| TreeFam | TF313433 | |
| ChiTaRS | IGBP1 | |
| GeneWiki | IGBP1 | |
| GenomeRNAi | 3476 | |
| NextBio | 13672 | |
| PRO | PR:P78318 | |
| Proteomes | UP000005640 | |
| Bgee | P78318 | |
| CleanEx | HS_IGBP1 | |
| Genevestigator | P78318 | |
| GO | GO:0005737 GO:0005874 GO:0008601 GO:0042113 GO:2001234 GO:0043154 GO:0035308 GO:0032873 GO:0000122 GO:0035306 GO:0045944 GO:0060632 GO:0070555 GO:0034612 GO:0007165 | |
| InterPro | IPR007304 | |
| PANTHER | PTHR10933 | |
| Pfam | PF04177 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0070555 |
response to interleukin-1 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060632 |
regulation of microtubule-based movement |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034612 |
response to tumor necrosis factor |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032873 |
negative regulation of stress-activated MAPK cascade |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019888 |
protein phosphatase regulator activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051721 |
protein phosphatase 2A binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000101130 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000101130 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043666 |
regulation of phosphoprotein phosphatase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0019888 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009966 |
regulation of signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042113 |
B cell activation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0048523 |
negative regulation of cellular process |
ECO:0000314 |
P |
Figure 1 |
complete | |||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Prickett, TD & Brautigan, DL (2007) Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3. Mol. Cell. Biol. 27 4217-27 PubMed GONUTS page
- ↑ Aranda-Orgillés, B et al. (2008) Active transport of the ubiquitin ligase MID1 along the microtubules is regulated by protein phosphatase 2A. PLoS ONE 3 e3507 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Chen, J et al. (1998) Alpha 4 associates with protein phosphatases 2A, 4, and 6. Biochem. Biophys. Res. Commun. 247 827-32 PubMed GONUTS page
- ↑ 4.0 4.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Gregers, TF et al. (2013) BiP negatively affects ricin transport. Toxins (Basel) 5 969-82 PubMed GONUTS page
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