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HUMAN:IFT88
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | IFT88 (synonyms: TG737, TTC10) | |
Protein Name(s) | Intraflagellar transport protein 88 homolog
Recessive polycystic kidney disease protein Tg737 homolog Tetratricopeptide repeat protein 10 TPR repeat protein 10 | |
External Links | ||
UniProt | Q13099 | |
EMBL | U20362 AK300769 AL161772 AL590096 AL590096 AL161772 AL161772 AL590096 AL590096 AL161772 CH471075 BC030776 | |
CCDS | CCDS31944.1 CCDS31945.1 | |
RefSeq | NP_006522.2 NP_783195.2 XP_005266610.1 XP_006719932.1 XP_006719933.1 | |
UniGene | Hs.187376 | |
ProteinModelPortal | Q13099 | |
SMR | Q13099 | |
BioGrid | 113771 | |
IntAct | Q13099 | |
STRING | 9606.ENSP00000323580 | |
PhosphoSite | Q13099 | |
DMDM | 206729873 | |
MaxQB | Q13099 | |
PaxDb | Q13099 | |
PRIDE | Q13099 | |
DNASU | 8100 | |
Ensembl | ENST00000319980 ENST00000351808 | |
GeneID | 8100 | |
KEGG | hsa:8100 | |
UCSC | uc001unh.3 | |
CTD | 8100 | |
GeneCards | GC13P021141 | |
HGNC | HGNC:20606 | |
HPA | HPA040731 | |
MIM | 600595 | |
neXtProt | NX_Q13099 | |
Orphanet | 474 564 | |
PharmGKB | PA134991804 | |
eggNOG | COG0457 | |
GeneTree | ENSGT00390000015473 | |
HOGENOM | HOG000258203 | |
HOVERGEN | HBG059328 | |
InParanoid | Q13099 | |
KO | K16474 | |
OMA | LILCYYA | |
OrthoDB | EOG7N37D5 | |
PhylomeDB | Q13099 | |
TreeFam | TF313218 | |
Reactome | REACT_267634 | |
ChiTaRS | IFT88 | |
GeneWiki | IFT88 | |
GenomeRNAi | 8100 | |
NextBio | 30744 | |
PRO | PR:Q13099 | |
Proteomes | UP000005640 | |
Bgee | Q13099 | |
CleanEx | HS_IFT88 | |
ExpressionAtlas | Q13099 | |
Genevestigator | Q13099 | |
GO | GO:0002080 GO:0045177 GO:0097541 GO:0005814 GO:0036064 GO:0097546 GO:0097542 GO:0005929 GO:0030992 GO:0060091 GO:0031514 GO:0031512 GO:0032391 GO:0009952 GO:0055007 GO:0060411 GO:0060271 GO:0090102 GO:0031122 GO:0007368 GO:0042733 GO:0036334 GO:0008544 GO:0003382 GO:0001654 GO:0048853 GO:0060914 GO:0060122 GO:0001822 GO:0001889 GO:0060426 GO:0050680 GO:0007219 GO:0060021 GO:0031016 GO:0043568 GO:0008104 GO:2000785 GO:1902017 GO:0045598 GO:0042487 GO:0070613 GO:0008589 GO:0034405 GO:0007224 GO:0007288 GO:0007290 GO:0021513 GO:0021537 | |
Gene3D | 1.25.40.10 | |
InterPro | IPR006597 IPR013026 IPR011990 IPR001440 IPR013105 IPR019734 | |
Pfam | PF00515 PF07719 PF13174 PF13181 | |
SMART | SM00671 SM00028 | |
PROSITE | PS50005 PS50293 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0036126 |
sperm flagellum |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0036064 |
ciliary basal body |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005813 |
centrosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005929 |
cilium |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0036064 |
ciliary basal body |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0036064 |
ciliary basal body |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005814 |
centriole |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030992 |
intraciliary transport particle B |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0031514 |
motile cilium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030992 |
intraciliary transport particle B |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000785 |
regulation of autophagosome assembly |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1902017 |
regulation of cilium assembly |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0060271 |
cilium assembly |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0036064 |
ciliary basal body |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005929 |
cilium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005814 |
centriole |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:1905515 |
non-motile cilium assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0016919 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0097730 |
non-motile cilium |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0016919 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0097546 |
ciliary base |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98715 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060122 |
inner ear receptor cell stereocilium organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98715 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0036064 |
ciliary basal body |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98715 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0019894 |
kinesin binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98715 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005814 |
centriole |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98715 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001822 |
kidney development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98715 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005929 |
cilium |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0097542 |
ciliary tip |
Reactome:R-HSA-5625426 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
involved_in |
GO:0035735 |
intraciliary transport involved in cilium assembly |
Reactome:R-HSA-5620924 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005929 |
cilium |
Reactome:R-HSA-5625426 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005929 |
cilium |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0031514 |
motile cilium |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030030 |
cell projection organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005814 |
centriole |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005815 |
microtubule organizing center |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Yu, F et al. (2016) The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis. Sci Rep 6 35399 PubMed GONUTS page
- ↑ 2.0 2.1 Nishijima, Y et al. (2017) RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly. Mol. Biol. Cell 28 1652-1666 PubMed GONUTS page
- ↑ Kanie, T et al. (2017) The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev. Cell 42 22-36.e12 PubMed GONUTS page
- ↑ Nechipurenko, IV et al. (2016) A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis. Dev. Cell 38 493-506 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Kobayashi, T et al. (2014) The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly. J. Cell Biol. 204 215-29 PubMed GONUTS page
c
- Catarrhini
- GO:0042995 ! cell projection
- GO:0030030 ! cell projection organization
- GO:0005814 ! centriole
- GO:0005813 ! centrosome
- Chordata
- GO:0036064 ! ciliary basal body
- GO:0097546 ! ciliary base
- GO:0097542 ! ciliary tip
- GO:0005929 ! cilium
- GO:0060271 ! cilium assembly
- Craniata
- GO:0005737 ! cytoplasm
- GO:0005856 ! cytoskeleton
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