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HUMAN:GSTA2

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) GSTA2 (synonyms: GST2)
Protein Name(s) Glutathione S-transferase A2

GST HA subunit 2 GST class-alpha member 2 GST-gamma GSTA2-2 GTH2

External Links
UniProt P09210
EMBL M16594
S45640
S45627
S45629
S45636
S45637
S45639
X65727
X65728
X65729
X65730
X65731
X65732
AL109918
BC002895
CCDS CCDS4944.1
PIR S24330
S29658
RefSeq NP_000837.3
XP_011512834.1
UniGene Hs.94107
PDB 1AGS
2VCT
2WJU
4ACS
PDBsum 1AGS
2VCT
2WJU
4ACS
ProteinModelPortal P09210
SMR P09210
BioGrid 109194
IntAct P09210
STRING 9606.ENSP00000420168
BindingDB P09210
ChEMBL CHEMBL2241
DrugBank DB00993
DB01008
DB00608
DB00636
DB00903
DB00143
DB00163
iPTMnet P09210
PhosphoSitePlus P09210
BioMuta GSTA2
DMDM 126302551
REPRODUCTION-2DPAGE IPI00745233
MaxQB P09210
PaxDb P09210
PeptideAtlas P09210
PRIDE P09210
ProteomicsDB 52206
DNASU 2939
Ensembl ENST00000493422
GeneID 2939
KEGG hsa:2939
UCSC uc003pay.4
CTD 2939
DisGeNET 2939
EuPathDB HostDB:ENSG00000244067.2
GeneCards GSTA2
H-InvDB HIX0200871
HGNC HGNC:4627
HPA HPA004342
HPA048934
HPA053817
MIM 138360
neXtProt NX_P09210
OpenTargets ENSG00000244067
PharmGKB PA29017
eggNOG KOG1695
ENOG4111VAU
GeneTree ENSGT00670000097856
HOGENOM HOG000115734
HOVERGEN HBG053749
InParanoid P09210
KO K00799
OMA CPPAEKD
OrthoDB EOG091G0O3D
PhylomeDB P09210
TreeFam TF105321
BioCyc MetaCyc:HS01846-MONOMER
BRENDA 2.5.1.18
Reactome R-HSA-156590
R-HSA-8950505
SABIO-RK P09210
EvolutionaryTrace P09210
GeneWiki GSTA2
GenomeRNAi 2939
PRO PR:P09210
Proteomes UP000005640
Bgee ENSG00000244067
CleanEx HS_GSTA2
ExpressionAtlas P09210
GO GO:0005829
GO:0070062
GO:0004364
GO:0030855
GO:1901687
GO:0006749
GO:0035722
InterPro IPR010987
IPR036282
IPR004045
IPR003080
IPR004046
IPR036249
Pfam PF14497
PF02798
PRINTS PR01266
SUPFAM SSF47616
SSF52833
PROSITE PS50405
PS50404

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0070062

extracellular exosome

PMID:23533145[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0030855

epithelial cell differentiation

PMID:21492153[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

results_in_acquisition_of_features_of:(CL:1000334)

Seeded From UniProt

complete

involved_in

GO:0006749

glutathione metabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08263

P

Seeded From UniProt

complete

enables

GO:0004364

glutathione transferase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08263

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004364

glutathione transferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003080

F

Seeded From UniProt

complete

enables

GO:0004364

glutathione transferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.5.1.18

F

Seeded From UniProt

complete

enables

GO:0004364

glutathione transferase activity

PMID:3138230[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:1901687

glutathione derivative biosynthetic process

Reactome:R-HSA-156590

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

Reactome:R-HSA-8950586

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0035722

interleukin-12-mediated signaling pathway

Reactome:R-HSA-9020591

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-176054

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
  2. Buhrke, T et al. (2011) Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2. Dev. Growth Differ. 53 411-26 PubMed GONUTS page
  3. Chow, NW et al. (1988) Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate specificities. J. Biol. Chem. 263 12797-800 PubMed GONUTS page