HUMAN:GRIK2

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	GRIK2 (synonyms: GLUR6)
Protein Name(s)	Glutamate receptor ionotropic, kainate 2 GluK2 Excitatory amino acid receptor 4 EAA4 Glutamate receptor 6 GluR-6 GluR6
External Links
UniProt	Q13002
EMBL	U16126 AJ252246 AJ301608 AJ301609 AJ301610 HM149335 HM149336 HM149337 HM149338 HM149339 AL109919 AP002528 AP002529 AP002530 CH471051
CCDS	CCDS5048.1 CCDS5049.1 CCDS55045.1
PIR	A54260
RefSeq	NP_001159719.1 NP_068775.1 NP_786944.1 XP_005267002.1 XP_006715528.1
UniGene	Hs.98262
PDB	3QXM
PDBsum	3QXM
ProteinModelPortal	Q13002
SMR	Q13002
BioGrid	109155
IntAct	Q13002
STRING	9606.ENSP00000397026
BindingDB	Q13002
ChEMBL	CHEMBL3038480
DrugBank	DB01351 DB01352 DB00237 DB00241 DB01353 DB01354 DB01355 DB00849 DB00312 DB01174 DB00794 DB00418 DB00306 DB00599
GuidetoPHARMACOLOGY	451
PhosphoSite	Q13002
DMDM	2492627
MaxQB	Q13002
PaxDb	Q13002
PRIDE	Q13002
DNASU	2898
Ensembl	ENST00000369138 ENST00000413795 ENST00000421544
GeneID	2898
KEGG	hsa:2898
UCSC	uc003pqn.3 uc003pqo.4 uc010kcw.3 uc021zdk.1
CTD	2898
GeneCards	GC06P101846
H-InvDB	HIX0006094
HGNC	HGNC:4580
HPA	CAB022463 HPA014395 HPA014623
MIM	138244 611092
neXtProt	NX_Q13002
Orphanet	88616
PharmGKB	PA164741600
eggNOG	NOG316680
GeneTree	ENSGT00760000118920
HOVERGEN	HBG051839
InParanoid	Q13002
KO	K05202
OMA	IQRINIH
OrthoDB	EOG71G9W6
PhylomeDB	Q13002
TreeFam	TF334668
Reactome	REACT_21343 REACT_21346
SignaLink	Q13002
GeneWiki	GRIK2
GenomeRNAi	2898
NextBio	11469
PRO	PR:Q13002
Proteomes	UP000005640
Bgee	Q13002
CleanEx	HS_GRIK2
ExpressionAtlas	Q13002
Genevestigator	Q13002
GO	GO:0030054 GO:0030425 GO:0032839 GO:0005887 GO:0032983 GO:0043204 GO:0005886 GO:0014069 GO:0045211 GO:0042734 GO:0043195 GO:0005234 GO:0015277 GO:0001662 GO:0006874 GO:0007215 GO:0006886 GO:0034220 GO:0035235 GO:0043524 GO:0051967 GO:0051402 GO:0019228 GO:0043525 GO:0050806 GO:0043113 GO:0060079 GO:0060080 GO:0046328 GO:0048169 GO:0048172 GO:0050804 GO:0007268 GO:0035249 GO:0006810
InterPro	IPR001828 IPR019594 IPR001508 IPR001320 IPR028082
Pfam	PF01094 PF00060 PF10613
PRINTS	PR00177
SMART	SM00918 SM00079
SUPFAM	SSF53822

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0005234	extracellularly glutamate-gated ion channel activity	PMID:28180184^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0050806	positive regulation of synaptic transmission	PMID:15537878^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0050804	modulation of chemical synaptic transmission	PMID:15537878^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0048172	regulation of short-term neuronal synaptic plasticity	PMID:15537878^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0015277	kainate selective glutamate receptor activity	PMID:15537878^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95815 PANTHER:PTN001826301	F	Seeded From UniProt	complete
involved_in	GO:0050804	modulation of chemical synaptic transmission	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001826301 UniProtKB:Q13002	P	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004620 FB:FBgn0020429 MGI:MGI:95813 MGI:MGI:95815 MGI:MGI:95817 MGI:MGI:95818 PANTHER:PTN001826301 RGD:68366 RGD:68368	C	Seeded From UniProt	complete
part_of	GO:0042734	presynaptic membrane	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95814 MGI:MGI:95815 MGI:MGI:95817 MGI:MGI:95818 PANTHER:PTN001826307	C	Seeded From UniProt	complete
involved_in	GO:0035249	synaptic transmission, glutamatergic	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004620 FB:FBgn0020429 FB:FBgn0039916 MGI:MGI:95813 MGI:MGI:95814 MGI:MGI:95815 MGI:MGI:95818 PANTHER:PTN001826301	P	Seeded From UniProt	complete
part_of	GO:0032983	kainate selective glutamate receptor complex	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95814 MGI:MGI:95815 MGI:MGI:95817 MGI:MGI:95818 PANTHER:PTN001826307	C	Seeded From UniProt	complete
enables	GO:0015277	kainate selective glutamate receptor activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95814 MGI:MGI:95815 MGI:MGI:95818 PANTHER:PTN001826307 RGD:2732 RGD:2733 RGD:2735 UniProtKB:P39086 UniProtKB:Q13002 UniProtKB:Q13003 UniProtKB:Q16478	F	Seeded From UniProt	complete
enables	GO:0008066	glutamate receptor activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004620 PANTHER:PTN001826301 RGD:2733 RGD:2735 RGD:71027	F	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004620 FB:FBgn0052704 MGI:MGI:95808 MGI:MGI:95813 MGI:MGI:95816 PANTHER:PTN000437926 RGD:621531 TAIR:locus:2207165 UniProtKB:Q12879 UniProtKB:Q13224 UniProtKB:Q16478 WB:WBGene00001612	C	Seeded From UniProt	complete
involved_in	GO:0034220	ion transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005216	P	Seeded From UniProt	complete
involved_in	GO:0035235	ionotropic glutamate receptor signaling pathway	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004970	P	Seeded From UniProt	complete
involved_in	GO:0035235	ionotropic glutamate receptor signaling pathway	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004970	P	Seeded From UniProt	complete
involved_in	GO:0035235	ionotropic glutamate receptor signaling pathway	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0015277	P	Seeded From UniProt	complete
involved_in	GO:0035235	ionotropic glutamate receptor signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015277	P	Seeded From UniProt	complete
involved_in	GO:0035235	ionotropic glutamate receptor signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015277	P	Seeded From UniProt	complete
involved_in	GO:0035235	ionotropic glutamate receptor signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015277	P	Seeded From UniProt	complete
involved_in	GO:0099505	regulation of presynaptic membrane potential	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0099507	P	Seeded From UniProt	complete
enables	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	F	Seeded From UniProt	complete
enables	GO:0099507	ligand-gated ion channel activity involved in regulation of presynaptic membrane potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	F	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
part_of	GO:0098686	hippocampal mossy fiber to CA3 synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
involved_in	GO:0060080	inhibitory postsynaptic potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
involved_in	GO:0060079	excitatory postsynaptic potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
involved_in	GO:0051967	negative regulation of synaptic transmission, glutamatergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
involved_in	GO:0048172	regulation of short-term neuronal synaptic plasticity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
involved_in	GO:0048169	regulation of long-term neuronal synaptic plasticity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
involved_in	GO:0043524	negative regulation of neuron apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
part_of	GO:0042734	presynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
involved_in	GO:0042391	regulation of membrane potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
involved_in	GO:0035249	synaptic transmission, glutamatergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
part_of	GO:0032983	kainate selective glutamate receptor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
involved_in	GO:0019228	neuronal action potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
enables	GO:0015277	kainate selective glutamate receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	F	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	C	Seeded From UniProt	complete
involved_in	GO:0007268	chemical synaptic transmission	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
involved_in	GO:0006874	cellular calcium ion homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
enables	GO:0004970	ionotropic glutamate receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	F	Seeded From UniProt	complete
involved_in	GO:0001662	behavioral fear response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P39087 ensembl:ENSMUSP00000151921	P	Seeded From UniProt	complete
involved_in	GO:0051967	negative regulation of synaptic transmission, glutamatergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	P	Seeded From UniProt	complete
involved_in	GO:0051402	neuron apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	P	Seeded From UniProt	complete
involved_in	GO:0046328	regulation of JNK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	P	Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	C	Seeded From UniProt	complete
involved_in	GO:0043525	positive regulation of neuron apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	P	Seeded From UniProt	complete
part_of	GO:0043204	perikaryon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	C	Seeded From UniProt	complete
part_of	GO:0043195	terminal bouton	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	C	Seeded From UniProt	complete
involved_in	GO:0043113	receptor clustering	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	F	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	F	Seeded From UniProt	complete
part_of	GO:0032839	dendrite cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	C	Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	F	Seeded From UniProt	complete
enables	GO:0031624	ubiquitin conjugating enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	F	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	C	Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	C	Seeded From UniProt	complete
enables	GO:0030165	PDZ domain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	F	Seeded From UniProt	complete
enables	GO:0015277	kainate selective glutamate receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	F	Seeded From UniProt	complete
part_of	GO:0008328	ionotropic glutamate receptor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	C	Seeded From UniProt	complete
enables	GO:0008066	glutamate receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	F	Seeded From UniProt	complete
involved_in	GO:0007268	chemical synaptic transmission	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P42260 ensembl:ENSRNOP00000068172	C	Seeded From UniProt	complete
enables	GO:0004970	ionotropic glutamate receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001320 InterPro:IPR019594	F	Seeded From UniProt	complete
enables	GO:0005216	ion channel activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001508	F	Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001508	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001320 InterPro:IPR001508 InterPro:IPR019594	C	Seeded From UniProt	complete
enables	GO:0038023	signaling receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001508	F	Seeded From UniProt	complete
enables	GO:0015277	kainate selective glutamate receptor activity	PMID:7536611^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0007268	chemical synaptic transmission	PMID:7536611^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007215	glutamate receptor signaling pathway	PMID:7536611^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:7536611^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-451311 Reactome:R-HSA-451310 Reactome:R-HSA-451309 Reactome:R-HSA-451283	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C	Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0406	P	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0628 UniProtKB-SubCell:SL-0219	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Guzmán, YF et al. (2017) A gain-of-function mutation in the gene causes neurodevelopmental deficits. Neurol Genet 3 e129 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Breustedt, J & Schmitz, D (2004) Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses. J. Neurosci. 24 10093-8 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Hoo, KH et al. (1994) Functional expression and pharmacological characterization of the human EAA4 (GluR6) glutamate receptor: a kainate selective channel subunit. Recept. Channels 2 327-37 PubMed GONUTS page

[PMID:28180184-1] Guzmán, YF et al. (2017) A gain-of-function mutation in the gene causes neurodevelopmental deficits. Neurol Genet 3 e129 PubMed GONUTS page

[PMID:15537878-2] 2.0 ^2.1 ^2.2 ^2.3 Breustedt, J & Schmitz, D (2004) Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses. J. Neurosci. 24 10093-8 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:7536611-4] 4.0 ^4.1 ^4.2 ^4.3 Hoo, KH et al. (1994) Functional expression and pharmacological characterization of the human EAA4 (GluR6) glutamate receptor: a kainate selective channel subunit. Recept. Channels 2 327-37 PubMed GONUTS page

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HUMAN:GRIK2

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