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HUMAN:GPR3

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) GPR3 (synonyms: ACCA)
Protein Name(s) G-protein coupled receptor 3

ACCA orphan receptor

External Links
UniProt P46089
EMBL U18550
L32831
X83956
AK291185
AK314868
AL096774
CH471059
BC032702
U13668
CCDS CCDS303.1
PIR A55689
RefSeq NP_005272.1
UniGene Hs.66542
ProteinModelPortal P46089
SMR P46089
BioGrid 109088
IntAct P46089
STRING 9606.ENSP00000363136
GuidetoPHARMACOLOGY 83
DMDM 1170006
PaxDb P46089
PRIDE P46089
DNASU 2827
Ensembl ENST00000374024
GeneID 2827
KEGG hsa:2827
UCSC uc001bod.4
CTD 2827
GeneCards GC01P027719
H-InvDB HIX0160062
HGNC HGNC:4484
HPA CAB006254
MIM 600241
neXtProt NX_P46089
PharmGKB PA28872
eggNOG NOG320944
GeneTree ENSGT00760000118804
HOGENOM HOG000294075
HOVERGEN HBG079561
InParanoid P46089
KO K04311
OMA LWAICCC
OrthoDB EOG7966H0
PhylomeDB P46089
TreeFam TF330052
GeneWiki GPR3
GenomeRNAi 2827
NextBio 11155
PRO PR:P46089
Proteomes UP000005640
Bgee P46089
CleanEx HS_GPR3
ExpressionAtlas P46089
Genevestigator P46089
GO GO:0005887
GO:0004930
GO:0007189
GO:0030816
GO:0007204
GO:0040020
InterPro IPR000276
IPR017452
IPR000984
IPR000723
Pfam PF00001
PRINTS PR00237
PR00648
PR00644
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0120162

positive regulation of cold-induced thermogenesis

PMID:26455425[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35413

P

Seeded From UniProt

complete

involved_in

GO:0120162

positive regulation of cold-induced thermogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P35413
ensembl:ENSMUSP00000101531

P

Seeded From UniProt

complete

involved_in

GO:0040020

regulation of meiotic nuclear division

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P35413
ensembl:ENSMUSP00000101531

P

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276

F

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276
InterPro:IPR000723
InterPro:IPR000984
InterPro:IPR017452

C

Seeded From UniProt

complete

involved_in

GO:0007189

adenylate cyclase-activating G protein-coupled receptor signaling pathway

PMID:7639700[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:7639700[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

PMID:7639700[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Godlewski, G et al. (2015) Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue. Sci Rep 5 14953 PubMed GONUTS page
  2. 2.0 2.1 2.2 Eggerickx, D et al. (1995) Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase. Biochem. J. 309 ( Pt 3) 837-43 PubMed GONUTS page