GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:GCC2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) GCC2 (synonyms: KIAA0336, RANBP2L4)
Protein Name(s) GRIP and coiled-coil domain-containing protein 2

185 kDa Golgi coiled-coil protein GCC185 CLL-associated antigen KW-11 CTCL tumor antigen se1-1 Ran-binding protein 2-like 4 RanBP2L4 Renal carcinoma antigen NY-REN-53

External Links
UniProt Q8IWJ2
EMBL AB002334
AC012487
AC068941
CH471182
BC037774
BC146789
AF432211
AF273042
CCDS CCDS33268.1
RefSeq NP_852118.1
XP_006712934.1
UniGene Hs.436505
Hs.469630
PDB 3BBP
PDBsum 3BBP
ProteinModelPortal Q8IWJ2
SMR Q8IWJ2
BioGrid 115006
IntAct Q8IWJ2
STRING 9606.ENSP00000307939
PhosphoSite Q8IWJ2
DMDM 313104307
MaxQB Q8IWJ2
PaxDb Q8IWJ2
PRIDE Q8IWJ2
Ensembl ENST00000309863
ENST00000482325
GeneID 9648
KEGG hsa:9648
UCSC uc002tec.3
CTD 9648
GeneCards GC02P109065
H-InvDB HIX0023314
HGNC HGNC:23218
HPA HPA035849
MIM 612711
neXtProt NX_Q8IWJ2
PharmGKB PA134876902
eggNOG NOG12793
GeneTree ENSGT00730000111134
HOGENOM HOG000060191
HOVERGEN HBG045522
InParanoid Q8IWJ2
OMA HNEKEKS
PhylomeDB Q8IWJ2
TreeFam TF332907
EvolutionaryTrace Q8IWJ2
GeneWiki GCC2
GenomeRNAi 9648
NextBio 36215
PRO PR:Q8IWJ2
Proteomes UP000005640
Bgee Q8IWJ2
CleanEx HS_GCC2
ExpressionAtlas Q8IWJ2
Genevestigator Q8IWJ2
GO GO:0005737
GO:0005794
GO:0016020
GO:0005634
GO:0005802
GO:0042802
GO:0090161
GO:0034499
GO:0034453
GO:0031023
GO:0034067
GO:0000042
GO:0006622
GO:0071955
GO:0070861
GO:0042147
Gene3D 1.10.220.60
InterPro IPR000237
Pfam PF01465
SMART SM00755
PROSITE PS50913

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0016020

membrane

PMID:19946888[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0090161

Golgi ribbon formation

PMID:17488291[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0090161

Golgi ribbon formation

PMID:16885419[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071955

recycling endosome to Golgi transport

PMID:17488291[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0070861

regulation of protein exit from endoplasmic reticulum

PMID:17488291[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

NOT|involved_in

GO:0043001

Golgi to plasma membrane protein transport

PMID:16885419[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042147

retrograde transport, endosome to Golgi

PMID:17488291[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034499

late endosome to Golgi transport

PMID:16885419[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034453

microtubule anchoring

PMID:17543864[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034067

protein localization to Golgi apparatus

PMID:16885419[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034067

protein localization to Golgi apparatus

PMID:17488291[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031023

microtubule organizing center organization

PMID:17543864[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006622

protein targeting to lysosome

PMID:16885419[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005802

trans-Golgi network

PMID:16885419[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005802

trans-Golgi network

PMID:17488291[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:18243103[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0090161

Golgi ribbon formation

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431562
UniProtKB:Q8IWJ2

P

Seeded From UniProt

complete

involved_in

GO:0071955

recycling endosome to Golgi transport

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431562
UniProtKB:Q8IWJ2

P

Seeded From UniProt

complete

involved_in

GO:0070861

regulation of protein exit from endoplasmic reticulum

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431562
UniProtKB:Q8IWJ2

P

Seeded From UniProt

complete

involved_in

GO:0034499

late endosome to Golgi transport

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431562
UniProtKB:Q8IWJ2

P

Seeded From UniProt

complete

involved_in

GO:0034067

protein localization to Golgi apparatus

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431562
UniProtKB:Q8IWJ2

P

Seeded From UniProt

complete

involved_in

GO:0031023

microtubule organizing center organization

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431562
UniProtKB:Q8IWJ2

P

Seeded From UniProt

complete

involved_in

GO:0006622

protein targeting to lysosome

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431562
UniProtKB:Q8IWJ2

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431562
UniProtKB:Q8IWJ2

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0037979
PANTHER:PTN000431517
UniProtKB:Q08378
UniProtKB:Q8IWJ2

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431517
ZFIN:ZDB-GENE-110517-1

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000431519
UniProtKB:Q08378
UniProtKB:Q14980
UniProtKB:Q8IWJ2
UniProtKB:Q9UPV0

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:18243103[5]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q8IWJ2

F

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-6814682
Reactome:R-HSA-6814674
Reactome:R-HSA-6814671
Reactome:R-HSA-6814091
Reactome:R-HSA-6811431

ECO:0000304

author statement supported by traceable reference used in manual assertion





C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333
UniProtKB-SubCell:SL-0132

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Derby, MC et al. (2007) The trans-Golgi network golgin, GCC185, is required for endosome-to-Golgi transport and maintenance of Golgi structure. Traffic 8 758-73 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Reddy, JV et al. (2006) A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling. Mol. Biol. Cell 17 4353-63 PubMed GONUTS page
  4. ↑ 4.0 4.1 Efimov, A et al. (2007) Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network. Dev. Cell 12 917-30 PubMed GONUTS page
  5. ↑ 5.0 5.1 Burguete, AS et al. (2008) Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. Cell 132 286-98 PubMed GONUTS page
  6. ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=HUMAN:GCC2&oldid=5942198"