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HUMAN:FYCO1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | FYCO1 (synonyms: ZFYVE7) | |
| Protein Name(s) | FYVE and coiled-coil domain-containing protein 1
Zinc finger FYVE domain-containing protein 7 | |
| External Links | ||
| UniProt | Q9BQS8 | |
| EMBL | AJ292348 AL833308 AL832358 AC099782 BC007218 BC101468 BC101470 BC143368 AK023397 AK074165 | |
| CCDS | CCDS2734.1 | |
| RefSeq | NP_078789.2 XP_006713396.1 XP_006713397.1 XP_006713398.1 | |
| UniGene | Hs.200227 Hs.739775 | |
| ProteinModelPortal | Q9BQS8 | |
| SMR | Q9BQS8 | |
| BioGrid | 122669 | |
| DIP | DIP-60600N | |
| IntAct | Q9BQS8 | |
| MINT | MINT-8385159 | |
| STRING | 9606.ENSP00000296137 | |
| PhosphoSite | Q9BQS8 | |
| DMDM | 322510128 | |
| MaxQB | Q9BQS8 | |
| PaxDb | Q9BQS8 | |
| PRIDE | Q9BQS8 | |
| Ensembl | ENST00000296137 ENST00000535325 | |
| GeneID | 79443 | |
| KEGG | hsa:79443 | |
| UCSC | uc003cpb.5 uc011bal.1 | |
| CTD | 79443 | |
| GeneCards | GC03M045934 | |
| H-InvDB | HIX0003244 | |
| HGNC | HGNC:14673 | |
| HPA | HPA035526 | |
| MIM | 607182 610019 | |
| neXtProt | NX_Q9BQS8 | |
| Orphanet | 98991 | |
| PharmGKB | PA28453 | |
| eggNOG | NOG262828 | |
| GeneTree | ENSGT00730000110715 | |
| HOVERGEN | HBG063805 | |
| InParanoid | Q9BQS8 | |
| OMA | NNEALEG | |
| OrthoDB | EOG7Z0JVJ | |
| PhylomeDB | Q9BQS8 | |
| TreeFam | TF341788 | |
| ChiTaRS | FYCO1 | |
| GenomeRNAi | 79443 | |
| NextBio | 35481191 | |
| PRO | PR:Q9BQS8 | |
| Proteomes | UP000005640 | |
| Bgee | Q9BQS8 | |
| CleanEx | HS_FYCO1 | |
| ExpressionAtlas | Q9BQS8 | |
| Genevestigator | Q9BQS8 | |
| GO | GO:0005776 GO:0031410 GO:0016021 GO:0005770 GO:0005764 GO:0016020 GO:0046872 GO:0072383 | |
| Gene3D | 3.30.40.10 | |
| InterPro | IPR009038 IPR004012 IPR000306 IPR017455 IPR011011 IPR013083 | |
| Pfam | PF01363 PF02759 | |
| SMART | SM00064 | |
| SUPFAM | SSF101576 SSF57903 | |
| PROSITE | PS50866 PS50826 PS50178 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:1901098 |
positive regulation of autophagosome maturation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0072383 |
plus-end-directed vesicle transport along microtubule |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005776 |
autophagosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005770 |
late endosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901098 |
positive regulation of autophagosome maturation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002928874 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0072383 |
plus-end-directed vesicle transport along microtubule |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002928874 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005776 |
autophagosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002928874 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005770 |
late endosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002928874 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002928874 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005768 |
endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005776 |
autophagosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Olsvik, HL et al. (2015) FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy. J. Biol. Chem. 290 29361-74 PubMed GONUTS page
- ↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Pankiv, S et al. (2010) FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. J. Cell Biol. 188 253-69 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
