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HUMAN:FUT1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) FUT1 (synonyms: H, HSC)
Protein Name(s) Galactoside 2-alpha-L-fucosyltransferase 1

Alpha(1,2)FT 1 Blood group H alpha 2-fucosyltransferase Fucosyltransferase 1 GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1

External Links
UniProt P19526
EMBL M35531
Z69587
AB004861
AB004862
AB004863
AY923051
BC074732
CCDS CCDS12733.1
PIR A36047
RefSeq NP_000139.1
UniGene Hs.69747
ProteinModelPortal P19526
BioGrid 108799
STRING 9606.ENSP00000312021
CAZy GT11
PhosphoSite P19526
PaxDb P19526
PRIDE P19526
DNASU 2523
Ensembl ENST00000310160
GeneID 2523
KEGG hsa:2523
UCSC uc002pkk.3
CTD 2523
GeneCards GC19M049251
HGNC HGNC:4012
MIM 211100
neXtProt NX_P19526
PharmGKB PA28428
eggNOG NOG17447
HOGENOM HOG000261621
HOVERGEN HBG004338
InParanoid P19526
KO K00718
OMA FLHIHQD
OrthoDB EOG7C5M8F
PhylomeDB P19526
TreeFam TF315810
BRENDA 2.4.1.69
UniPathway UPA00378
GeneWiki FUT1
GenomeRNAi 2523
NextBio 9933
PRO PR:P19526
Proteomes UP000005640
Bgee P19526
CleanEx HS_FUT1
ExpressionAtlas P19526
Genevestigator P19526
GO GO:0005794
GO:0032580
GO:0005887
GO:0016020
GO:0008417
GO:0008107
GO:0005975
GO:0042355
GO:0006486
InterPro IPR002516
PANTHER PTHR11927
Pfam PF01531

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0042355

L-fucose catabolic process

PMID:11698403[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0036065

fucosylation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109375
PANTHER:PTN000231475

P

Seeded From UniProt

complete

enables

GO:0008107

galactoside 2-alpha-L-fucosyltransferase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109374
MGI:MGI:109375
MGI:MGI:1928893
PANTHER:PTN000231475
RGD:2639

F

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109374
MGI:MGI:1928893
PANTHER:PTN000231475

P

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002516

P

Seeded From UniProt

complete

enables

GO:0008107

galactoside 2-alpha-L-fucosyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002516

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002516

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:2118655[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0008417

fucosyltransferase activity

PMID:2118655[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

PMID:2118655[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:2118655[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:2118655[3]
PMID:11698403[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

enables

GO:0008107

galactoside 2-alpha-L-fucosyltransferase activity

PMID:11698403[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

PMID:11698403[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0328

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0032580

Golgi cisterna membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0136

C

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00378

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Roos, C et al. (2002) Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. J. Biol. Chem. 277 3168-75 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Larsen, RD et al. (1990) Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen. Proc. Natl. Acad. Sci. U.S.A. 87 6674-8 PubMed GONUTS page