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HUMAN:F161A

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) FAM161A
Protein Name(s) Protein FAM161A
External Links
UniProt Q3B820
EMBL BX648834
BX649029
AC107081
AK023367
AK296255
BC107162
BC107163
CCDS CCDS42687.2
CCDS56120.1
RefSeq NP_001188472.1
NP_115556.2
XP_006712177.1
UniGene Hs.440466
ProteinModelPortal Q3B820
BioGrid 123909
IntAct Q3B820
STRING 9606.ENSP00000385893
PhosphoSite Q3B820
DMDM 182705173
MaxQB Q3B820
PaxDb Q3B820
PRIDE Q3B820
DNASU 84140
Ensembl ENST00000404929
ENST00000405894
GeneID 84140
KEGG hsa:84140
UCSC uc002sbm.4
uc002sbn.4
CTD 84140
GeneCards GC02M062051
GeneReviews FAM161A
H-InvDB HIX0002084
HGNC HGNC:25808
HPA HPA032119
MIM 606068
613596
neXtProt NX_Q3B820
Orphanet 791
PharmGKB PA162386876
eggNOG NOG80167
GeneTree ENSGT00530000063901
HOGENOM HOG000049209
HOVERGEN HBG107870
InParanoid Q3B820
KO K16772
OMA AEKHYSN
PhylomeDB Q3B820
TreeFam TF321199
GenomeRNAi 84140
NextBio 73449
PRO PR:Q3B820
Proteomes UP000005640
Bgee Q3B820
CleanEx HS_FAM161A
ExpressionAtlas Q3B820
Genevestigator Q3B820
GO GO:0005813
GO:0036064
GO:0005737
GO:0032391
GO:0042384
GO:0050896
GO:0007601
InterPro IPR019579
Pfam PF10595

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042802

identical protein binding

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008017

microtubule binding

PMID:22791751[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0000235

astral microtubule

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0097431

mitotic spindle pole

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0072686

mitotic spindle

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005813

centrosome

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0036064

ciliary basal body

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005876

spindle microtubule

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0001917

photoreceptor inner segment

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:1901985

positive regulation of protein acetylation

PMID:22791751[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_at:(GO:0005874)

Seeded From UniProt

complete

involved_in

GO:0060271

cilium assembly

PMID:22940612[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0036064

ciliary basal body

PMID:22940612[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032391

photoreceptor connecting cilium

PMID:22940612[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005813

centrosome

PMID:21399614[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0044782

cilium organization

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1921123
PANTHER:PTN001088555

P

Seeded From UniProt

complete

colocalizes_with

GO:0036064

ciliary basal body

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1921123
PANTHER:PTN000487251
RGD:1304999
UniProtKB:Q3B820

C

Seeded From UniProt

complete

part_of

GO:0032391

photoreceptor connecting cilium

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1921123
PANTHER:PTN000487251
RGD:1304999
UniProtKB:Q3B820

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:25416956[5]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q3B820

F

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0005929

cilium

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0969
UniProtKB-SubCell:SL-0066

C

Seeded From UniProt

complete

involved_in

GO:0030030

cell projection organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0970

P

Seeded From UniProt

complete

involved_in

GO:0050896

response to stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0716

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

involved_in

GO:0007601

visual perception

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0844

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Zach, F et al. (2012) The retinitis pigmentosa 28 protein FAM161A is a novel ciliary protein involved in intermolecular protein interaction and microtubule association. Hum. Mol. Genet. 21 4573-86 PubMed GONUTS page
  2. 2.0 2.1 2.2 Di Gioia, SA et al. (2012) FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies. Hum. Mol. Genet. 21 5174-84 PubMed GONUTS page
  3. Jakobsen, L et al. (2011) Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J. 30 1520-35 PubMed GONUTS page
  4. 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  5. Rolland, T et al. (2014) A proteome-scale map of the human interactome network. Cell 159 1212-26 PubMed GONUTS page