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HUMAN:ENW1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ERVW-1 (synonyms: ERVWE1) | |
| Protein Name(s) | HERV-W_7q21.2 provirus ancestral Env polyprotein
Endogenous retrovirus group W member 1 Env-W Envelope polyprotein gPr73 Enverin HERV-7q Envelope protein HERV-W envelope protein Syncytin Syncytin-1 Surface protein SU gp50 Transmembrane protein TM gp24 | |
| External Links | ||
| UniProt | Q9UQF0 | |
| EMBL | AF072503 AF072505 AF072506 AF072508 AF208161 AF513360 AF156963 AC007566 AY101582 AY101583 AY101584 AY101585 AF520478 AF520480 AF520482 AF520484 AF520486 AF520488 AF520490 AF520492 AF520494 AF520496 AF520498 AF520500 AF520502 AF520504 AF520506 AF520508 AF520510 AF520512 AF520514 AF520516 AF520518 AF520520 AF520522 AF520524 AF520526 AF520528 AF520530 AF520532 AF520534 AF520536 AF520538 AF520540 AF520542 AF520544 AF520546 AF520548 AF520550 AF520552 AF520554 AF520556 AF520558 AF520560 AF520562 AF520564 BC137381 AF506835 | |
| CCDS | CCDS5626.1 | |
| RefSeq | NP_001124397.1 NP_055405.3 | |
| ProteinModelPortal | Q9UQF0 | |
| SMR | Q9UQF0 | |
| BioGrid | 119040 | |
| STRING | 9606.ENSP00000419945 | |
| TCDB | 1.G.9.1.1 | |
| PhosphoSite | Q9UQF0 | |
| DMDM | 47605755 | |
| PaxDb | Q9UQF0 | |
| PRIDE | Q9UQF0 | |
| Ensembl | ENST00000493463 ENST00000603053 | |
| GeneID | 30816 | |
| KEGG | hsa:30816 | |
| UCSC | uc022ahe.1 | |
| CTD | 30816 | |
| GeneCards | GC07M092098 | |
| HGNC | HGNC:13525 | |
| MIM | 604659 | |
| neXtProt | NX_Q9UQF0 | |
| PharmGKB | PA27878 | |
| eggNOG | NOG131568 | |
| HOVERGEN | HBG051487 | |
| InParanoid | Q9UQF0 | |
| OMA | HANTHYW | |
| OrthoDB | EOG70ZZQM | |
| PhylomeDB | Q9UQF0 | |
| TreeFam | TF332233 | |
| ChiTaRS | ERVW-1 | |
| GeneWiki | ERVWE1 | |
| GenomeRNAi | 30816 | |
| NextBio | 52878 | |
| PRO | PR:Q9UQF0 | |
| ArrayExpress | Q9UQF0 | |
| Bgee | Q9UQF0 | |
| Genevestigator | Q9UQF0 | |
| GO | GO:0016021 GO:0005886 GO:0019031 GO:0009653 GO:0006949 | |
| InterPro | IPR018154 | |
| PANTHER | PTHR10424 | |
| Pfam | PF00429 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0000768 |
syncytium formation by plasma membrane fusion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006949 |
syncytium formation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009653 |
anatomical structure morphogenesis |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0001948 |
glycoprotein binding |
ECO:0000314 |
F |
Figure 3 |
complete | |||||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Blaise, S et al. (2003) Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution. Proc. Natl. Acad. Sci. U.S.A. 100 13013-8 PubMed GONUTS page
- ↑ Sugimoto, J et al. (2013) A novel human endogenous retroviral protein inhibits cell-cell fusion. Sci Rep 3 1462 PubMed GONUTS page
- ↑ Mi, S et al. (2000) Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis. Nature 403 785-9 PubMed GONUTS page
- ↑ Antony, JM et al. (2004) Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination. Nat. Neurosci. 7 1088-95 PubMed GONUTS page
