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HUMAN:DPP2
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | DPP7 (synonyms: DPP2, QPP) | |
| Protein Name(s) | Dipeptidyl peptidase 2
Dipeptidyl aminopeptidase II Dipeptidyl peptidase 7 Dipeptidyl peptidase II DPP II Quiescent cell proline dipeptidase | |
| External Links | ||
| UniProt | Q9UHL4 | |
| EMBL | AF154502 AK292112 AL929554 BC011907 BC016961 | |
| CCDS | CCDS7030.1 | |
| PIR | S77568 | |
| RefSeq | NP_037511.2 | |
| UniGene | Hs.37916 | |
| PDB | 3JYH 3N0T 4EBB | |
| PDBsum | 3JYH 3N0T 4EBB | |
| ProteinModelPortal | Q9UHL4 | |
| SMR | Q9UHL4 | |
| BioGrid | 118989 | |
| IntAct | Q9UHL4 | |
| STRING | 9606.ENSP00000360635 | |
| BindingDB | Q9UHL4 | |
| ChEMBL | CHEMBL2111469 | |
| GuidetoPHARMACOLOGY | 1605 | |
| MEROPS | S28.002 | |
| PhosphoSite | Q9UHL4 | |
| DMDM | 212276510 | |
| MaxQB | Q9UHL4 | |
| PaxDb | Q9UHL4 | |
| PRIDE | Q9UHL4 | |
| DNASU | 29952 | |
| Ensembl | ENST00000371579 | |
| GeneID | 29952 | |
| KEGG | hsa:29952 | |
| UCSC | uc004clh.3 | |
| CTD | 29952 | |
| GeneCards | GC09M140004 | |
| H-InvDB | HIX0017204 HIX0025819 | |
| HGNC | HGNC:14892 | |
| HPA | CAB025541 HPA021282 | |
| MIM | 610537 | |
| neXtProt | NX_Q9UHL4 | |
| PharmGKB | PA27469 | |
| eggNOG | NOG290141 | |
| GeneTree | ENSGT00530000063027 | |
| HOGENOM | HOG000238311 | |
| HOVERGEN | HBG005526 | |
| InParanoid | Q9UHL4 | |
| KO | K01276 | |
| OMA | LVSEKFW | |
| OrthoDB | EOG78WKRN | |
| PhylomeDB | Q9UHL4 | |
| TreeFam | TF314414 | |
| ChiTaRS | DPP7 | |
| EvolutionaryTrace | Q9UHL4 | |
| GeneWiki | DPP7 | |
| GenomeRNAi | 29952 | |
| NextBio | 52649 | |
| PRO | PR:Q9UHL4 | |
| Proteomes | UP000005640 | |
| Bgee | Q9UHL4 | |
| CleanEx | HS_DPP7 | |
| ExpressionAtlas | Q9UHL4 | |
| Genevestigator | Q9UHL4 | |
| GO | GO:0016023 GO:0005829 GO:0070062 GO:0005764 GO:0008239 GO:0008236 | |
| Gene3D | 3.40.50.1820 | |
| InterPro | IPR029058 IPR008758 | |
| PANTHER | PTHR11010 | |
| Pfam | PF05577 | |
| SUPFAM | SSF53474 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0031982 |
vesicle |
ECO:0000314 |
C |
figure 5 shows through confocal microscopy, localization of QPP (DPP2) to the vesicles. |
complete | |||||
|
part_of |
GO:0031982 |
vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031982 |
vesicle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000110173 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008239 |
dipeptidyl-peptidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000110021 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000110021 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008239 |
dipeptidyl-peptidase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPB1 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPB1 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPB1 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008236 |
serine-type peptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008236 |
serine-type peptidase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043312 |
neutrophil degranulation |
Reactome:R-HSA-6798695 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0035578 |
azurophil granule lumen |
Reactome:R-HSA-6798751 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
Reactome:R-HSA-6798751 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004177 |
aminopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008236 |
serine-type peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Chiravuri, M et al. (2000) Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase. J. Immunol. 165 5695-702 PubMed GONUTS page
- ↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Underwood, R et al. (1999) Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase. J. Biol. Chem. 274 34053-8 PubMed GONUTS page
