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HUMAN:DPP10
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | DPP10 (synonyms: DPRP3, KIAA1492) | |
| Protein Name(s) | Inactive dipeptidyl peptidase 10
Dipeptidyl peptidase IV-related protein 3 DPRP-3 Dipeptidyl peptidase X DPP X Dipeptidyl peptidase-like protein 2 DPL2 | |
| External Links | ||
| UniProt | Q8N608 | |
| EMBL | AY387785 AY172661 AB040925 DQ857322 AK289967 AC010885 AC012071 AC016721 AC017040 AC066593 AC067947 AC068542 AC093610 AC105422 AC116620 AC118276 AC118664 BC030832 | |
| CCDS | CCDS33278.1 CCDS46400.1 CCDS54388.1 CCDS54389.1 | |
| RefSeq | NP_001004360.2 NP_001171505.1 NP_065919.2 | |
| UniGene | Hs.580539 | |
| ProteinModelPortal | Q8N608 | |
| SMR | Q8N608 | |
| BioGrid | 121672 | |
| IntAct | Q8N608 | |
| STRING | 9606.ENSP00000386565 | |
| MEROPS | S09.974 | |
| PhosphoSite | Q8N608 | |
| DMDM | 296434483 | |
| MaxQB | Q8N608 | |
| PaxDb | Q8N608 | |
| PRIDE | Q8N608 | |
| DNASU | 57628 | |
| Ensembl | ENST00000310323 ENST00000393147 ENST00000409163 ENST00000410059 | |
| GeneID | 57628 | |
| KEGG | hsa:57628 | |
| UCSC | uc002tle.3 | |
| CTD | 57628 | |
| GeneCards | GC02P115295 | |
| HGNC | HGNC:20823 | |
| HPA | HPA048767 | |
| MIM | 600807 608209 | |
| neXtProt | NX_Q8N608 | |
| PharmGKB | PA134991647 | |
| eggNOG | COG1506 | |
| GeneTree | ENSGT00760000119233 | |
| HOVERGEN | HBG105877 | |
| InParanoid | Q8N608 | |
| OMA | KEGIIFN | |
| OrthoDB | EOG7H791M | |
| PhylomeDB | Q8N608 | |
| TreeFam | TF313309 | |
| ChiTaRS | DPP10 | |
| GeneWiki | DPP10 | |
| GenomeRNAi | 57628 | |
| NextBio | 35535176 | |
| PRO | PR:Q8N608 | |
| Proteomes | UP000005640 | |
| Bgee | Q8N608 | |
| CleanEx | HS_DPP10 | |
| ExpressionAtlas | Q8N608 | |
| Genevestigator | Q8N608 | |
| GO | GO:0016021 GO:0016020 GO:0008236 | |
| Gene3D | 2.140.10.30 3.40.50.1820 | |
| InterPro | IPR029058 IPR001375 IPR002469 | |
| Pfam | PF00930 PF00326 | |
| SUPFAM | SSF53474 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0090004 |
positive regulation of establishment of protein localization in plasma membrane |
ECO:0000314 |
P |
Figure 1d showed that DPP10 facilitated cell membrane surface expression of Kv4.2 protein through in situ hybridization. accession #:AY172661 |
complete | |||||
|
part_of |
GO:0008076 |
voltage-gated potassium channel complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0044325 |
ion channel binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015459 |
potassium channel regulator activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901379 |
regulation of potassium ion transmembrane transport |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0072659 |
protein localization to plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1903078 |
positive regulation of protein localization to plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
NOT|enables |
GO:0008239 |
dipeptidyl-peptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008236 |
serine-type peptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Zagha, E et al. (2005) DPP10 modulates Kv4-mediated A-type potassium channels. J. Biol. Chem. 280 18853-61 PubMed GONUTS page
- ↑ 2.0 2.1 Shiina, Y et al. (2016) Fly DPP10 acts as a channel ancillary subunit and possesses peptidase activity. Sci Rep 6 26290 PubMed GONUTS page
- ↑ 3.0 3.1 Qi, SY et al. (2003) Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases. Biochem. J. 373 179-89 PubMed GONUTS page
p
- GO:0005886 ! plasma membrane
- GO:1903078 ! positive regulation of protein localization to plasma membrane
- GO:0090004 ! positive regulation of establishment of protein localization to plasma membrane
- GO:0015459 ! potassium channel regulator activity
- Primates
- GO:0072659 ! protein localization to plasma membrane
- GO:0006508 ! proteolysis
