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HUMAN:DIRA3

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) DIRAS3 (synonyms: ARHI, NOEY2, RHOI)
Protein Name(s) GTP-binding protein Di-Ras3

Distinct subgroup of the Ras family member 3 Rho-related GTP-binding protein RhoI

External Links
UniProt O95661
EMBL U96750
AF202543
CR541870
CR541892
AK021882
AL157407
CH471059
BC005362
CCDS CCDS641.1
RefSeq NP_004666.1
XP_006711090.1
UniGene Hs.194695
ProteinModelPortal O95661
SMR O95661
BioGrid 114534
IntAct O95661
STRING 9606.ENSP00000360020
PhosphoSite O95661
PaxDb O95661
PRIDE O95661
DNASU 9077
Ensembl ENST00000370981
ENST00000395201
GeneID 9077
KEGG hsa:9077
UCSC uc001ded.3
CTD 9077
GeneCards GC01M068511
HGNC HGNC:687
HPA HPA028483
HPA028557
HPA029384
MIM 605193
neXtProt NX_O95661
PharmGKB PA24980
eggNOG COG1100
GeneTree ENSGT00770000120482
HOGENOM HOG000233973
HOVERGEN HBG009351
InParanoid O95661
KO K07842
OMA ARGHAFI
OrthoDB EOG7SBNQ3
PhylomeDB O95661
TreeFam TF313014
GenomeRNAi 9077
NextBio 34013
PRO PR:O95661
Proteomes UP000005640
Bgee O95661
CleanEx HS_DIRAS3
Genevestigator O95661
GO GO:0005886
GO:0005525
GO:0003924
GO:0000079
GO:0006349
GO:0007264
Gene3D 3.40.50.300
InterPro IPR027417
IPR005225
IPR001806
IPR020849
PANTHER PTHR24070
Pfam PF00071
PRINTS PR00449
SUPFAM SSF52540
TIGRFAMs TIGR00231
PROSITE PS51421

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0003924

GTPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001806

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001806
InterPro:IPR005225
InterPro:IPR020849

F

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020849

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020849

C

Seeded From UniProt

complete

involved_in

GO:0007264

small GTPase mediated signal transduction

PMID:9874798[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006349

regulation of gene expression by genetic imprinting

PMID:9874798[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

PMID:9874798[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0000079

regulation of cyclin-dependent protein serine/threonine kinase activity

PMID:9874798[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Yu, Y et al. (1999) NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas. Proc. Natl. Acad. Sci. U.S.A. 96 214-9 PubMed GONUTS page