HUMAN:DBC1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	DBC1 (synonyms: DBCCR1, FAM5A)
Protein Name(s)	Deleted in bladder cancer protein 1 Protein FAM5A
External Links
UniProt	O60477
EMBL	AF027734 AL138894 AL353773 AL138894 AL353773 AL353773 AL138894 AL353773 AL138894 BC021560 BC065196 BC071702
IPI	IPI00005607 IPI00644682 IPI00719605
PIR	T09052
RefSeq	NP_055433.2
UniGene	Hs.532316
ProteinModelPortal	O60477
SMR	O60477
IntAct	O60477
STRING	9606.ENSP00000265922
PhosphoSite	O60477
PaxDb	O60477
PRIDE	O60477
Ensembl	ENST00000265922 ENST00000373964
GeneID	1620
KEGG	hsa:1620
UCSC	uc004bkc.2
CTD	1620
GeneCards	GC09M121915
H-InvDB	HIX0034750
HGNC	HGNC:2687
HPA	HPA038828
MIM	602865
neXtProt	NX_O60477
PharmGKB	PA27156
eggNOG	NOG83259
HOGENOM	HOG000049122
HOVERGEN	HBG081412
InParanoid	O60477
OMA	HSEGWSM
OrthoDB	EOG480HW3
PhylomeDB	O60477
GeneWiki	DBC1
GenomeRNAi	1620
NextBio	6650
PRO	PR:O60477
ArrayExpress	O60477
Bgee	O60477
CleanEx	HS_DBC1
Genevestigator	O60477
GO	GO:0005737 GO:0015630 GO:0007050 GO:0008219 GO:0045786
InterPro	IPR020864
Pfam	PF01823
SMART	SM00457
PROSITE	PS00279 PS51412

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0045786	negative regulation of cell cycle	PMID:11420708^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0008219	cell death	PMID:14712213^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:11420708^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0071300	cellular response to retinoic acid	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1928478 MGI:MGI:2443035 MGI:MGI:2443333 PANTHER:PTN001036861	P	Seeded From UniProt	complete
involved_in	GO:0045930	negative regulation of mitotic cell cycle	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1928478 MGI:MGI:2443035 MGI:MGI:2443333 PANTHER:PTN001036861	P	Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1928478 MGI:MGI:2443035 MGI:MGI:2443333 PANTHER:PTN001036861	P	Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001036861 RGD:708419 RGD:708421	C	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001036861 RGD:708419 RGD:708421	C	Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001036861 RGD:708419 RGD:708421	C	Seeded From UniProt	complete
involved_in	GO:0071625	vocalization behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0071300	cellular response to retinoic acid	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0050768	negative regulation of neurogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0045930	negative regulation of mitotic cell cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0042711	maternal behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0035640	exploration behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0007614	short-term memory	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0001662	behavioral fear response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q920P3 ensembl:ENSMUSP00000030036	P	Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033237	P	Seeded From UniProt	complete
involved_in	GO:0045930	negative regulation of mitotic cell cycle	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033237	P	Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P	Seeded From UniProt	complete
involved_in	GO:0007050	cell cycle arrest	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0338	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Nishiyama, H et al. (2001) Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1. Oncogene 20 2956-64 PubMed GONUTS page
↑ Wright, KO et al. (2004) DBCCR1 mediates death in cultured bladder tumor cells. Oncogene 23 82-90 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11420708-1] 1.0 ^1.1 Nishiyama, H et al. (2001) Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1. Oncogene 20 2956-64 PubMed GONUTS page

[PMID:14712213-2] Wright, KO et al. (2004) DBCCR1 mediates death in cultured bladder tumor cells. Oncogene 23 82-90 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

[2]

[3]

HUMAN:DBC1

Contents

Annotations

Notes

References

b

c

d

e

h

m

n

p

s

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools