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HUMAN:CRIM1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) CRIM1 (synonyms: S52)
Protein Name(s) Cysteine-rich motor neuron 1 protein

CRIM-1 Cysteine-rich repeat-containing protein S52 Processed cysteine-rich motor neuron 1 protein

External Links
UniProt Q9NZV1
EMBL AF167706
AF168681
AB209139
AY358371
BC111989
BC113371
CCDS CCDS1783.1
RefSeq NP_057525.1
UniGene Hs.699247
ProteinModelPortal Q9NZV1
SMR Q9NZV1
BioGrid 119395
DIP DIP-58932N
IntAct Q9NZV1
STRING 9606.ENSP00000280527
PhosphoSite Q9NZV1
DMDM 67460590
MaxQB Q9NZV1
PaxDb Q9NZV1
PeptideAtlas Q9NZV1
PRIDE Q9NZV1
Ensembl ENST00000280527
GeneID 51232
KEGG hsa:51232
UCSC uc002rpd.3
CTD 51232
GeneCards GC02P036583
H-InvDB HIX0030218
HGNC HGNC:2359
HPA HPA000556
MIM 606189
neXtProt NX_Q9NZV1
PharmGKB PA26877
eggNOG NOG283828
GeneTree ENSGT00760000119335
HOGENOM HOG000063671
HOVERGEN HBG081345
InParanoid Q9NZV1
OMA WREDDCT
PhylomeDB Q9NZV1
TreeFam TF106451
ChiTaRS CRIM1
GeneWiki CRIM1
GenomeRNAi 51232
NextBio 54338
PMAP-CutDB Q9NZV1
PRO PR:Q9NZV1
Proteomes UP000005640
Bgee Q9NZV1
CleanEx HS_CRIM1
ExpressionAtlas Q9NZV1
Genevestigator Q9NZV1
GO GO:0070062
GO:0016021
GO:0005886
GO:0005010
GO:0030165
GO:0004867
GO:0048009
GO:0007399
GO:0001558
Gene3D 2.10.22.10
InterPro IPR004094
IPR009030
IPR011061
IPR000867
IPR001007
Pfam PF02822
PF00093
SMART SM00121
SM00214
SUPFAM SSF57184
SSF57262
PROSITE PS51252
PS51323
PS01208
PS50184

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0030165

PDZ domain binding

PMID:23209302[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

GO:0005010

insulin-like growth factor-activated receptor activity

PMID:18669648[2]

ECO:0000315

F

Figure 2 shows a detailed analysis of phosphopeptides abundance distributions of different peptides and different cycles.

complete
CACAO 10096

involved_in

GO:0010951

negative regulation of endopeptidase activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004867

P

Seeded From UniProt

complete

involved_in

GO:0043086

negative regulation of catalytic activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004857

P

Seeded From UniProt

complete

involved_in

GO:0048009

insulin-like growth factor receptor signaling pathway

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005010

P

Seeded From UniProt

complete

enables

GO:0004857

enzyme inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011061

F

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004094

F

Seeded From UniProt

complete

enables

GO:0005520

insulin-like growth factor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000867

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000867

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:10642437[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

PMID:10642437[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005010

insulin-like growth factor-activated receptor activity

PMID:10642437[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Ahmed, SM et al. (2012) KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. J. Cell Biol. 199 951-67 PubMed GONUTS page
  2. Dephoure, N et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc. Natl. Acad. Sci. U.S.A. 105 10762-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 Kolle, G et al. (2000) CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis. Mech. Dev. 90 181-93 PubMed GONUTS page