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HUMAN:CNCG

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) PDE6H
Protein Name(s) Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

GMP-PDE gamma

External Links
UniProt Q13956
EMBL D45399
BC069774
BC069800
BC093738
BC093740
CCDS CCDS8672.1
RefSeq NP_006196.1
UniGene Hs.54471
ProteinModelPortal Q13956
SMR Q13956
BioGrid 111175
STRING 9606.ENSP00000266395
ChEMBL CHEMBL2363066
DrugBank DB00203
DB00862
PhosphoSite Q13956
DMDM 2833249
PaxDb Q13956
PRIDE Q13956
DNASU 5149
Ensembl ENST00000266395
GeneID 5149
KEGG hsa:5149
UCSC uc001rcr.3
CTD 5149
GeneCards GC12P015125
GeneReviews PDE6H
HGNC HGNC:8790
MIM 601190
610024
neXtProt NX_Q13956
Orphanet 49382
PharmGKB PA33138
eggNOG NOG44345
GeneTree ENSGT00390000013260
HOGENOM HOG000261673
HOVERGEN HBG000447
KO K13760
OMA NDIPLME
OrthoDB EOG7SN8FW
PhylomeDB Q13956
TreeFam TF333297
GenomeRNAi 5149
NextBio 19868
PRO PR:Q13956
Proteomes UP000005640
Bgee Q13956
CleanEx HS_PDE6H
Genevestigator Q13956
GO GO:0047555
GO:0030553
GO:0004857
GO:0000187
GO:0043086
GO:0045742
GO:0045745
GO:0050896
GO:0007601
Gene3D 4.10.1120.10
InterPro IPR006952
PANTHER PTHR12122
Pfam PF04868
PIRSF PIRSF000969

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0043086

negative regulation of catalytic activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004857

P

Seeded From UniProt

complete

involved_in

GO:0045745

positive regulation of G protein-coupled receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61249
ensembl:ENSMUSP00000119246

P

Seeded From UniProt

complete

involved_in

GO:0045742

positive regulation of epidermal growth factor receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61249
ensembl:ENSMUSP00000119246

P

Seeded From UniProt

complete

involved_in

GO:0000187

activation of MAPK activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61249
ensembl:ENSMUSP00000119246

P

Seeded From UniProt

complete

enables

GO:0004114

3',5'-cyclic-nucleotide phosphodiesterase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006952
InterPro:IPR037030

F

Seeded From UniProt

complete

involved_in

GO:0007601

visual perception

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006952
InterPro:IPR037030

P

Seeded From UniProt

complete

enables

GO:0030553

cGMP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006952
InterPro:IPR037030

F

Seeded From UniProt

complete

enables

GO:0047555

3',5'-cyclic-GMP phosphodiesterase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.4.35

F

Seeded From UniProt

complete

involved_in

GO:0007601

visual perception

PMID:8786098[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004857

enzyme inhibitor activity

PMID:8786098[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0050896

response to stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0716

P

Seeded From UniProt

complete

involved_in

GO:0007601

visual perception

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0844

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Shimizu-Matsumoto, A et al. (1996) Isolation and chromosomal localization of the human cone cGMP phosphodiesterase gamma cDNA (PDE6H). Genomics 32 121-4 PubMed GONUTS page