HUMAN:CKLF3

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	CMTM3 (synonyms: CKLFSF3)
Protein Name(s)	CKLF-like MARVEL transmembrane domain-containing protein 3 Chemokine-like factor superfamily member 3
External Links
UniProt	Q96MX0
EMBL	AF479813 AY166714 AK056324 AC018557 CH471092 BC023509 BC023591 BC036042 BC040227 BC047701
CCDS	CCDS10815.1
RefSeq	NP_653202.1 NP_853531.1 XP_006721194.1
UniGene	Hs.298198
ProteinModelPortal	Q96MX0
BioGrid	125844
IntAct	Q96MX0
MINT	MINT-8247569
STRING	9606.ENSP00000354579
PhosphoSitePlus	Q96MX0
SwissPalm	Q96MX0
BioMuta	CMTM3
DMDM	34922036
EPD	Q96MX0
MaxQB	Q96MX0
PaxDb	Q96MX0
PeptideAtlas	Q96MX0
PRIDE	Q96MX0
Ensembl	ENST00000361909 ENST00000424011 ENST00000562707 ENST00000565922 ENST00000567572
GeneID	123920
KEGG	hsa:123920
UCSC	uc002epu.5
CTD	123920
DisGeNET	123920
GeneCards	CMTM3
HGNC	HGNC:19174
HPA	HPA013870
MIM	607886
neXtProt	NX_Q96MX0
OpenTargets	ENSG00000140931
PharmGKB	PA38813
eggNOG	KOG4788 ENOG4111IAF
GeneTree	ENSGT00530000063326
HOVERGEN	HBG053619
InParanoid	Q96MX0
OMA	IIFICYI
OrthoDB	EOG091G11FO
PhylomeDB	Q96MX0
TreeFam	TF317387
ChiTaRS	CMTM3
GenomeRNAi	123920
PRO	PR:Q96MX0
Proteomes	UP000005640
Bgee	ENSG00000140931
CleanEx	HS_CMTM3
ExpressionAtlas	Q96MX0
Genevisible	Q96MX0
GO	GO:0005737 GO:0005615 GO:0016021 GO:0031965 GO:0006935 GO:0050861
InterPro	IPR008253
Pfam	PF01284
PROSITE	PS51225

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005829	cytosol	PMID:28428220	ECO:0000314			C		Fig. 5 Parts C, L and M details the colocalization of CKLF3 with CDH5 throughout the endothelial cytosol. The organism of the gene used is human, and the gene is referred to as CMTM3 in the experiment while UniProt refers to it as CKLF3. The colocalized protein, CDH5, is referred to as VE-cadherin throughout the experiment and as CDH5 by UniProt, with accession P33151.	complete CACAO 12742
	GO:0031410	cytoplasmic vesicle	PMID:28428220	ECO:0000314			C		Fig. 5 Part B shows CKLF3 localizing in cytoplasmic vesicle-like structures. The organism is human, and the gene is referred to as CMTM3 throughout the experiment while it is referred to as CKLF3 by UniProt.	complete CACAO 12743
part_of	GO:0016021	integral component of membrane		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001103553 UniProtKB:Q9UBR5	C		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005125	P		Seeded From UniProt	complete
involved_in	GO:0050861	positive regulation of B cell receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99LJ5 ensembl:ENSMUSP00000034343	P		Seeded From UniProt	complete
part_of	GO:0031965	nuclear membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99LJ5 ensembl:ENSMUSP00000034343	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99LJ5 ensembl:ENSMUSP00000034343	C		Seeded From UniProt	complete
involved_in	GO:0001835	blastocyst hatching	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99LJ5 ensembl:ENSMUSP00000034343	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008253	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0202	C		Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0202	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0145	P		Seeded From UniProt	complete
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References

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