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HUMAN:CAH8
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | CA8 (synonyms: CALS) | |
| Protein Name(s) | Carbonic anhydrase-related protein
CARP Carbonic anhydrase VIII CA-VIII | |
| External Links | ||
| UniProt | P35219 | |
| EMBL | L04656 AY075022 AK289470 AK314538 AK090655 CH471068 BC069744 BC069794 BC108929 | |
| CCDS | CCDS6174.1 | |
| PIR | JN0576 | |
| RefSeq | NP_001308766.1 NP_001308767.1 NP_001308768.1 NP_004047.3 | |
| PDB | 2W2J | |
| PDBsum | 2W2J | |
| SMR | P35219 | |
| BioGrid | 107222 | |
| IntAct | P35219 | |
| MINT | P35219 | |
| STRING | 9606.ENSP00000314407 | |
| DrugBank | DB00909 | |
| iPTMnet | P35219 | |
| PhosphoSitePlus | P35219 | |
| BioMuta | CA8 | |
| DMDM | 461681 | |
| EPD | P35219 | |
| jPOST | P35219 | |
| MassIVE | P35219 | |
| MaxQB | P35219 | |
| PaxDb | P35219 | |
| PeptideAtlas | P35219 | |
| PRIDE | P35219 | |
| ProteomicsDB | 54985 | |
| DNASU | 767 | |
| Ensembl | ENST00000317995 | |
| GeneID | 767 | |
| KEGG | hsa:767 | |
| UCSC | uc003xtz.2 | |
| CTD | 767 | |
| DisGeNET | 767 | |
| GeneCards | CA8 | |
| HGNC | HGNC:1382 | |
| HPA | CAB025545 CAB047309 HPA024748 | |
| MalaCards | CA8 | |
| MIM | 114815 613227 | |
| neXtProt | NX_P35219 | |
| OpenTargets | ENSG00000178538 | |
| Orphanet | 1766 | |
| PharmGKB | PA25997 | |
| eggNOG | KOG0382 COG3338 | |
| GeneTree | ENSGT00940000158863 | |
| HOGENOM | HOG000112637 | |
| InParanoid | P35219 | |
| KO | K01672 | |
| OMA | PSDHEYE | |
| OrthoDB | 1377476at2759 | |
| PhylomeDB | P35219 | |
| TreeFam | TF316425 | |
| BRENDA | 4.2.1.1 | |
| ChiTaRS | CA8 | |
| EvolutionaryTrace | P35219 | |
| GeneWiki | CA8 | |
| GenomeRNAi | 767 | |
| Pharos | P35219 | |
| PRO | PR:P35219 | |
| Proteomes | UP000005640 | |
| Bgee | ENSG00000178538 | |
| Genevisible | P35219 | |
| GO | GO:0005737 GO:0004089 GO:0008270 GO:0048015 | |
| CDD | cd03120 | |
| Gene3D | 3.10.200.10 | |
| InterPro | IPR001148 IPR036398 IPR023561 IPR018338 IPR041877 | |
| PANTHER | PTHR18952 | |
| Pfam | PF00194 | |
| SMART | SM01057 | |
| SUPFAM | SSF51069 | |
| PROSITE | PS00162 PS51144 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0048015 |
phosphatidylinositol-mediated signaling |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P28651 |
P |
Seeded From UniProt |
|||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P28651 |
C |
Seeded From UniProt |
|||
|
enables |
GO:0004089 |
carbonate dehydratase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0004089 |
carbonate dehydratase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0004089 |
carbonate dehydratase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
|
involved_in |
GO:0048015 |
phosphatidylinositol-mediated signaling |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P28651 |
P |
Seeded From UniProt |
|||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P28651 |
C |
Seeded From UniProt |
|||
|
enables |
GO:0004089 |
carbonate dehydratase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
| |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Sjöblom, B et al. (1996) Two point mutations convert a catalytically inactive carbonic anhydrase-related protein (CARP) to an active enzyme. FEBS Lett. 398 322-5 PubMed GONUTS page
- ↑ Yachie, N et al. (2016) Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Mol. Syst. Biol. 12 863 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Sahni, N et al. (2015) Widespread macromolecular interaction perturbations in human genetic disorders. Cell 161 647-660 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Rolland, T et al. (2014) A proteome-scale map of the human interactome network. Cell 159 1212-26 PubMed GONUTS page
