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HUMAN:C9JIR6

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) PPM1B (ECO:0000313 with Ensembl:ENSP00000390087)
Protein Name(s) Protein phosphatase 1B (ECO:0000313 with Ensembl:ENSP00000390087)
External Links
UniProt C9JIR6
EMBL AC013717
AC019129
ProteinModelPortal C9JIR6
SMR C9JIR6
BindingDB C9JIR6
PRIDE C9JIR6
Ensembl ENST00000419807
HGNC HGNC:9276
GeneTree ENSGT00740000115384
HOGENOM HOG000233895
OrthoDB EOG7WMCJH
ChiTaRS PPM1B
NextBio 35486653
Proteomes UP000005640
Bgee C9JIR6
ExpressionAtlas C9JIR6
GO GO:0000287
GO:0030145
GO:0004722
GO:0006470
Gene3D 1.10.10.430
3.60.40.10
InterPro IPR001932
IPR012911
IPR000222
IPR015655
PANTHER PTHR13832
Pfam PF00481
PF07830
SMART SM00331
SM00332
SUPFAM SSF81601
SSF81606
PROSITE PS01032

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006470

protein dephosphorylation

PMID:22750291[1]

ECO:0000315

P

Fig 3. PPM1B binds to and dephosphorylates TBK1.

complete
CACAO 5866

involved_in

GO:0006470

protein dephosphorylation

PMID:22750291[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012911
InterPro:IPR036580

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001932

F

Seeded From UniProt

complete

enables

GO:0004721

phosphoprotein phosphatase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012911
InterPro:IPR036580

F

Seeded From UniProt

complete

enables

GO:0004722

protein serine/threonine phosphatase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015655

F

Seeded From UniProt

complete

involved_in

GO:0006470

protein dephosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015655

P

Seeded From UniProt

complete

enables

GO:0030145

manganese ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012911
InterPro:IPR036580

F

Seeded From UniProt

complete

enables

GO:0043169

cation binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000222

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0004721

phosphoprotein phosphatase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0904

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Zhao, Y et al. (2012) PPM1B negatively regulates antiviral response via dephosphorylating TBK1. Cell. Signal. 24 2197-204 PubMed GONUTS page