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HUMAN:B3GLT

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) B3GLCT (ECO:0000312 with HGNC:HGNC:20207) (synonyms: B3GALTL, B3GTL)
Protein Name(s) Beta-1,3-glucosyltransferase

Beta3Glc-T Beta 3-glucosyltransferase (ECO:0000312 with HGNC:HGNC:20207) Beta-3-glycosyltransferase-like

External Links
UniProt Q6Y288
EMBL AY190526
AB101481
AK291273
AL137142
AL138965
CH471075
BC068595
CCDS CCDS9341.1
RefSeq NP_919299.3
UniGene Hs.13205
ProteinModelPortal Q6Y288
SMR Q6Y288
BioGrid 126890
IntAct Q6Y288
STRING 9606.ENSP00000343002
CAZy GT31
iPTMnet Q6Y288
PhosphoSitePlus Q6Y288
SwissPalm Q6Y288
BioMuta B3GLCT
DMDM 116243011
EPD Q6Y288
jPOST Q6Y288
MaxQB Q6Y288
PaxDb Q6Y288
PeptideAtlas Q6Y288
PRIDE Q6Y288
ProteomicsDB 67832
Ensembl ENST00000343307
GeneID 145173
KEGG hsa:145173
UCSC uc010aaz.4
CTD 145173
DisGeNET 145173
EuPathDB HostDB:ENSG00000187676.7
GeneCards B3GLCT
GeneReviews B3GLCT
H-InvDB HIX0011217
HGNC HGNC:20207
MalaCards B3GLCT
MIM 261540
610308
neXtProt NX_Q6Y288
OpenTargets ENSG00000187676
Orphanet 709
PharmGKB PA144596515
eggNOG ENOG410IE18
ENOG410XWFG
GeneTree ENSGT00940000155499
HOGENOM HOG000007375
HOVERGEN HBG059386
InParanoid Q6Y288
KO K13675
OMA PEFCTDD
OrthoDB 935669at2759
PhylomeDB Q6Y288
TreeFam TF313496
Reactome R-HSA-5083635
R-HSA-5173214
UniPathway UPA00378
ChiTaRS B3GLCT
GeneWiki B3GALTL
GenomeRNAi 145173
PRO PR:Q6Y288
Proteomes UP000005640
Bgee ENSG00000187676
Genevisible Q6Y288
GO GO:0005789
GO:0016021
GO:0008375
GO:0016757
GO:0006004
GO:0036066
InterPro IPR003378
IPR029044
Pfam PF02434
SUPFAM SSF53448
PROSITE PS00014

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:1990773

matrix metallopeptidase secretion

PMID:25544610[1]

ECO:0000018

P

Fig. 1 A and B show that B3GLCT is required for secretion of ADAMTSL1 and 2 and TSP1 targets in Human cells.

complete
CACAO 13651

enables

GO:0008375

acetylglucosaminyltransferase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0011591
PANTHER:PTN000087478

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003378

C

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003378

F

Seeded From UniProt

complete

involved_in

GO:0036066

protein O-linked fucosylation

Reactome:R-HSA-5173214

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

Reactome:R-HSA-5173005

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

Reactome:R-HSA-5173005

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0119

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0006004

fucose metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0294

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0328

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00378

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Vasudevan, D et al. (2015) Peters plus syndrome mutations disrupt a noncanonical ER quality-control mechanism. Curr. Biol. 25 286-95 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page