GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HUMAN:AQP7
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | AQP7 (synonyms: AQP7L, AQP9) | |
| Protein Name(s) | Aquaporin-7
AQP-7 Aquaglyceroporin-7 Aquaporin adipose AQPap Aquaporin-7-like | |
| External Links | ||
| UniProt | O14520 | |
| EMBL | AB006190 AB052626 AK300716 AK315879 AL356218 BC119672 BC119673 | |
| CCDS | CCDS6541.1 | |
| PIR | JC5791 | |
| RefSeq | NP_001161.1 XP_005251510.1 | |
| UniGene | Hs.455323 | |
| ProteinModelPortal | O14520 | |
| SMR | O14520 | |
| STRING | 9606.ENSP00000297988 | |
| GuidetoPHARMACOLOGY | 694 | |
| PRIDE | O14520 | |
| DNASU | 364 | |
| Ensembl | ENST00000297988 ENST00000447660 | |
| GeneID | 364 | |
| KEGG | hsa:364 | |
| UCSC | uc003zss.3 uc003zst.3 | |
| CTD | 364 | |
| GeneCards | GC09M033384 | |
| H-InvDB | HIX0008072 HIX0034850 HIX0034865 | |
| HGNC | HGNC:640 | |
| HPA | HPA044049 HPA048106 | |
| MIM | 602974 614411 | |
| neXtProt | NX_O14520 | |
| PharmGKB | PA24925 | |
| GeneTree | ENSGT00510000046311 | |
| HOVERGEN | HBG106057 | |
| InParanoid | O14520 | |
| KO | K08771 | |
| OMA | YQSGWIV | |
| PhylomeDB | O14520 | |
| TreeFam | TF313173 | |
| Reactome | REACT_23809 REACT_23826 | |
| GeneWiki | AQP7 | |
| GenomeRNAi | 364 | |
| NextBio | 1523 | |
| PRO | PR:O14520 | |
| Proteomes | UP000005640 | |
| Bgee | O14520 | |
| CleanEx | HS_AQP7 HS_AQP9 | |
| ExpressionAtlas | O14520 | |
| Genevestigator | O14520 | |
| GO | GO:0005911 GO:0005737 GO:0005887 GO:0005886 GO:0015254 GO:0015250 GO:0007588 GO:0006091 GO:0015793 GO:0055085 GO:0006833 | |
| Gene3D | 1.20.1080.10 | |
| InterPro | IPR023271 IPR015686 IPR000425 | |
| PANTHER | PTHR19139 PTHR19139:SF16 | |
| Pfam | PF00230 | |
| PRINTS | PR00783 | |
| SUPFAM | SSF81338 | |
| TIGRFAMs | TIGR00861 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0006833 |
water transport |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015254 |
glycerol channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015250 |
water channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015793 |
glycerol transport |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015254 |
glycerol channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015250 |
water channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015793 |
glycerol transport |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006833 |
water transport |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005911 |
cell-cell junction |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015204 |
urea transmembrane transporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000441001 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0015254 |
glycerol channel activity |
ECO:0000269 |
experimental evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071918 |
urea transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015204 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0015267 |
channel activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055085 |
transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015793 |
glycerol transport |
Reactome:R-HSA-432030 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006833 |
water transport |
Reactome:R-HSA-432047 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-507871 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Kondo, H et al. (2002) Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation. Eur. J. Biochem. 269 1814-26 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gotfryd, K et al. (2018) Human adipose glycerol flux is regulated by a pH gate in AQP10. Nat Commun 9 4749 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Rubenwolf, PC et al. (2009) Expression and localisation of aquaporin water channels in human urothelium in situ and in vitro. Eur. Urol. 56 1013-23 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Kuriyama, H et al. (1997) Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability. Biochem. Biophys. Res. Commun. 241 53-8 PubMed GONUTS page
