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HUMAN:AOFA
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | MAOA | |
| Protein Name(s) | Amine oxidase [flavin-containing] A
Monoamine oxidase type A MAO-A | |
| External Links | ||
| UniProt | P21397 | |
| EMBL | M69226 M68840 X60806 X60807 X60808 X60809 X60810 X60811 X60812 X60813 X60814 X60815 X60816 X60817 X60818 X60819 M68857 M68843 M68844 M68845 M68846 M68847 M68848 M68849 M68850 M68851 M68852 M68853 M68854 M68855 M68856 AK293926 AL109855 BX530072 BX537147 BX537148 BC008064 M89636 S81371 S72704 | |
| CCDS | CCDS14260.1 CCDS59163.1 | |
| PIR | A36175 | |
| RefSeq | NP_000231.1 NP_001257387.1 | |
| UniGene | Hs.183109 | |
| PDB | 1H8Q 2BXR 2BXS 2Z5X 2Z5Y | |
| PDBsum | 1H8Q 2BXR 2BXS 2Z5X 2Z5Y | |
| ProteinModelPortal | P21397 | |
| SMR | P21397 | |
| BioGrid | 110301 | |
| IntAct | P21397 | |
| MINT | MINT-4054607 | |
| STRING | 9606.ENSP00000340684 | |
| BindingDB | P21397 | |
| ChEMBL | CHEMBL1951 | |
| DrugBank | DB00918 DB00988 DB01363 DB03147 DB00614 DB01247 DB00601 DB01577 DB00805 DB01171 DB08804 DB00952 DB00184 DB01626 DB00780 DB00191 DB00388 DB00397 DB00721 DB00852 DB00140 DB00953 DB01037 DB01104 DB00669 DB00624 DB00752 DB00315 DB00909 | |
| GuidetoPHARMACOLOGY | 2489 | |
| PhosphoSite | P21397 | |
| DMDM | 113978 | |
| MaxQB | P21397 | |
| PaxDb | P21397 | |
| PeptideAtlas | P21397 | |
| PRIDE | P21397 | |
| DNASU | 4128 | |
| Ensembl | ENST00000338702 ENST00000542639 | |
| GeneID | 4128 | |
| KEGG | hsa:4128 | |
| UCSC | uc004dfy.4 | |
| CTD | 4128 | |
| GeneCards | GC0XP043515 | |
| HGNC | HGNC:6833 | |
| HPA | CAB009437 | |
| MIM | 300615 309850 | |
| neXtProt | NX_P21397 | |
| Orphanet | 3057 | |
| PharmGKB | PA236 | |
| eggNOG | COG1231 | |
| GeneTree | ENSGT00730000110903 | |
| HOGENOM | HOG000221615 | |
| HOVERGEN | HBG004255 | |
| InParanoid | P21397 | |
| KO | K00274 | |
| OMA | DAPWEAP | |
| OrthoDB | EOG7K6PTP | |
| PhylomeDB | P21397 | |
| TreeFam | TF313314 | |
| BioCyc | MetaCyc:HS01798-MONOMER | |
| BRENDA | 1.4.3.4 | |
| Reactome | REACT_15418 REACT_15511 REACT_15532 REACT_15548 REACT_416 | |
| SABIO-RK | P21397 | |
| ChiTaRS | MAOA | |
| EvolutionaryTrace | P21397 | |
| GeneWiki | Monoamine_oxidase_A | |
| GenomeRNAi | 4128 | |
| NextBio | 16206 | |
| PRO | PR:P21397 | |
| Proteomes | UP000005640 | |
| Bgee | P21397 | |
| CleanEx | HS_MAOA | |
| ExpressionAtlas | P21397 | |
| Genevestigator | P21397 | |
| GO | GO:0016021 GO:0005741 GO:0005739 GO:0008131 GO:0006576 GO:0042420 GO:0042136 GO:0042135 GO:0007269 GO:0044281 GO:0007268 GO:0006805 | |
| InterPro | IPR002937 IPR001613 | |
| Pfam | PF01593 | |
| PRINTS | PR00757 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001134) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042420 |
dopamine catabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64133 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009967 |
positive regulation of signal transduction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64133 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008131 |
primary amine oxidase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64133 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005741 |
mitochondrial outer membrane |
PMID:24252804[2] |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0042420 |
dopamine catabolic process |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
occurs_in:(GO:0005829) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006576 |
cellular biogenic amine metabolic process |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042133 |
neurotransmitter metabolic process |
Reactome:R-HSA-374909 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019221 |
cytokine-mediated signaling pathway |
Reactome:R-HSA-6785807 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042135 |
neurotransmitter catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006584 |
catecholamine metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Zhao, X et al. (2011) Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes. Mol. Cell Proteomics 10 M110.000299 PubMed GONUTS page
- ↑ 2.0 2.1 Dias, V et al. (2013) The role of oxidative stress in Parkinson's disease. J Parkinsons Dis 3 461-91 PubMed GONUTS page
- ↑ Brunner, HG et al. (1993) Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science 262 578-80 PubMed GONUTS page
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