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HUMAN:AL1B1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ALDH1B1 (synonyms: ALDH5, ALDHX) | |
| Protein Name(s) | Aldehyde dehydrogenase X, mitochondrial
Aldehyde dehydrogenase 5 Aldehyde dehydrogenase family 1 member B1 | |
| External Links | ||
| UniProt | P30837 | |
| EMBL | M63967 BT007418 AK313344 AL135785 BC001619 | |
| CCDS | CCDS6615.1 | |
| PIR | A40872 | |
| RefSeq | NP_000683.3 | |
| UniGene | Hs.436219 Hs.743532 | |
| ProteinModelPortal | P30837 | |
| SMR | P30837 | |
| BioGrid | 106721 | |
| IntAct | P30837 | |
| STRING | 9606.ENSP00000366927 | |
| ChEMBL | CHEMBL4881 | |
| PhosphoSite | P30837 | |
| DMDM | 311033472 | |
| REPRODUCTION-2DPAGE | IPI00103467 | |
| MaxQB | P30837 | |
| PaxDb | P30837 | |
| PRIDE | P30837 | |
| DNASU | 219 | |
| Ensembl | ENST00000377698 | |
| GeneID | 219 | |
| KEGG | hsa:219 | |
| UCSC | uc004aay.3 | |
| CTD | 219 | |
| GeneCards | GC09P038392 | |
| H-InvDB | HIX0008051 | |
| HGNC | HGNC:407 | |
| HPA | HPA021037 | |
| MIM | 100670 | |
| neXtProt | NX_P30837 | |
| PharmGKB | PA24695 | |
| eggNOG | COG1012 | |
| HOGENOM | HOG000271505 | |
| HOVERGEN | HBG000097 | |
| InParanoid | P30837 | |
| KO | K00128 | |
| OrthoDB | EOG7PS1F7 | |
| PhylomeDB | P30837 | |
| TreeFam | TF300455 | |
| SABIO-RK | P30837 | |
| UniPathway | UPA00780 | |
| ChiTaRS | ALDH1B1 | |
| GeneWiki | ALDH1B1 | |
| GenomeRNAi | 219 | |
| NextBio | 886 | |
| PRO | PR:P30837 | |
| Proteomes | UP000005640 | |
| Bgee | P30837 | |
| CleanEx | HS_ALDH1B1 | |
| ExpressionAtlas | P30837 | |
| Genevestigator | P30837 | |
| GO | GO:0043231 GO:0005759 GO:0005739 GO:0005634 GO:0004029 GO:0005975 GO:0006068 | |
| Gene3D | 3.40.309.10 3.40.605.10 | |
| InterPro | IPR016161 IPR016163 IPR016160 IPR029510 IPR016162 IPR015590 | |
| Pfam | PF00171 | |
| SUPFAM | SSF53720 | |
| PROSITE | PS00070 PS00687 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004029 |
aldehyde dehydrogenase (NAD) activity |
ECO:0000314 |
F |
Table 1: The gels were stained for ALDH activity with an agar overlay containing propionaldehyde or benzaldehyde. |
complete | |||||
|
enables |
GO:0051287 |
NAD binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0005975 |
carbohydrate metabolic process |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004029 |
aldehyde dehydrogenase (NAD) activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0012036 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR015590 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016620 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR015590 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043878 |
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004029 |
aldehyde dehydrogenase (NAD) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006069 |
ethanol oxidation |
Reactome:R-HSA-71384 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005759 |
mitochondrial matrix |
Reactome:R-HSA-5696091 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006068 |
ethanol catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00780 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kassner, EG et al. (1977) Passage of feeding catheters into the pleural space: a radiographic sign of trauma to the pharynx and esophagus in the newborn. AJR Am J Roentgenol 128 19-22 PubMed GONUTS page
- ↑ Bateman, OA et al. (2003) Crystal structure of eta-crystallin: adaptation of a class 1 aldehyde dehydrogenase for a new role in the eye lens. Biochemistry 42 4349-56 PubMed GONUTS page
- ↑ Yoshida, A (1992) Molecular genetics of human aldehyde dehydrogenase. Pharmacogenetics 2 139-47 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
