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HUMAN:ADPGK
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ADPGK | |
| Protein Name(s) | ADP-dependent glucokinase
ADP-GK ADPGK RbBP-35 | |
| External Links | ||
| UniProt | Q9BRR6 | |
| EMBL | AF204270 AL136873 AK055526 CR533447 AK075560 BC006112 BC018074 | |
| CCDS | CCDS42057.1 | |
| RefSeq | NP_112574.3 XP_006720775.1 XP_006720778.1 | |
| UniGene | Hs.654636 | |
| ProteinModelPortal | Q9BRR6 | |
| SMR | Q9BRR6 | |
| BioGrid | 123643 | |
| IntAct | Q9BRR6 | |
| MINT | MINT-1404876 | |
| STRING | 9606.ENSP00000312250 | |
| PhosphoSite | Q9BRR6 | |
| DMDM | 62899887 | |
| MaxQB | Q9BRR6 | |
| PaxDb | Q9BRR6 | |
| PRIDE | Q9BRR6 | |
| DNASU | 83440 | |
| Ensembl | ENST00000311669 ENST00000456471 ENST00000562823 ENST00000567941 ENST00000569517 | |
| GeneID | 83440 | |
| KEGG | hsa:83440 | |
| UCSC | uc002ave.4 uc002avf.4 uc002avg.4 | |
| CTD | 83440 | |
| GeneCards | GC15M073043 | |
| H-InvDB | HIX0026868 | |
| HGNC | HGNC:25250 | |
| HPA | HPA045194 | |
| MIM | 611861 | |
| neXtProt | NX_Q9BRR6 | |
| PharmGKB | PA134971928 | |
| eggNOG | COG4809 | |
| GeneTree | ENSGT00390000017953 | |
| HOGENOM | HOG000233731 | |
| HOVERGEN | HBG050461 | |
| InParanoid | Q9BRR6 | |
| KO | K08074 | |
| OMA | GVNACVD | |
| PhylomeDB | Q9BRR6 | |
| TreeFam | TF313401 | |
| UniPathway | UPA00109 | |
| ChiTaRS | ADPGK | |
| GeneWiki | ADP-specific_glucokinase | |
| GenomeRNAi | 83440 | |
| NextBio | 72318 | |
| PRO | PR:Q9BRR6 | |
| Proteomes | UP000005640 | |
| Bgee | Q9BRR6 | |
| CleanEx | HS_ADPGK | |
| ExpressionAtlas | Q9BRR6 | |
| Genevestigator | Q9BRR6 | |
| GO | GO:0005576 GO:0016020 GO:0043843 GO:0046872 GO:0006096 | |
| Gene3D | 3.40.1190.20 | |
| InterPro | IPR007666 IPR029056 | |
| PANTHER | PTHR21208 | |
| Pfam | PF04587 | |
| SUPFAM | SSF53613 | |
| PROSITE | PS51255 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005783 |
endoplasmic reticulum |
ECO:0000314 |
C |
Figure 4E. |
complete | |||||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043843 |
ADP-specific glucokinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006006 |
glucose metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0005975 |
carbohydrate metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016773 |
phosphotransferase activity, alcohol group as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043843 |
ADP-specific glucokinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061621 |
canonical glycolysis |
Reactome:R-HSA-70171 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
Reactome:R-HSA-5696021 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006096 |
glycolytic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0324 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Kamiński, MM et al. (2012) T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation. Cell Rep 2 1300-15 PubMed GONUTS page
- ↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
- ↑ 3.0 3.1 Richter, JP et al. (2016) The Structural and Functional Characterization of Mammalian ADP-dependent Glucokinase. J. Biol. Chem. 291 3694-704 PubMed GONUTS page
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