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HUMAN:ACTH

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) ACTG2 (synonyms: ACTA3, ACTL3, ACTSG)
Protein Name(s) Actin, gamma-enteric smooth muscle

Alpha-actin-3 Gamma-2-actin Smooth muscle gamma-actin

External Links
UniProt P63267
EMBL X16940
D00654
AK304523
AK312955
CR536515
CR541794
AC073046
CH471053
BC012617
BC094877
CCDS CCDS1930.1
CCDS56124.1
PIR A40261
RefSeq NP_001186822.1
NP_001606.1
UniGene Hs.516105
ProteinModelPortal P63267
SMR P63267
BioGrid 106587
IntAct P63267
MINT MINT-256943
STRING 9606.ENSP00000295137
PhosphoSite P63267
BioMuta ACTG2
DMDM 54036679
OGP P12718
MaxQB P63267
PRIDE P63267
DNASU 72
Ensembl ENST00000345517
ENST00000409624
ENST00000409731
GeneID 72
KEGG hsa:72
UCSC uc002sjw.3
CTD 72
GeneCards GC02P074119
HGNC HGNC:145
HPA HPA041264
HPA041271
MIM 102545
155310
neXtProt NX_P63267
Orphanet 2604
2241
104077
PharmGKB PA24469
GeneTree ENSGT00760000118957
HOGENOM HOG000233340
HOVERGEN HBG003771
InParanoid P63267
KO K12315
OMA ATLAMCE
PhylomeDB P63267
TreeFam TF354237
Reactome REACT_20558
SignaLink P63267
ChiTaRS ACTG2
GeneWiki ACTG2
GenomeRNAi 72
NextBio 20816142
PMAP-CutDB P63267
PRO PR:P63267
Proteomes UP000005640
Bgee P63267
CleanEx HS_ACTG2
ExpressionAtlas P63267
Genevisible P63267
GO GO:0072562
GO:0044297
GO:0071944
GO:0005737
GO:0005829
GO:0070062
GO:0005615
GO:0030175
GO:0030027
GO:0032982
GO:0005524
GO:0090131
GO:0006936
GO:0010628
InterPro IPR004000
IPR020902
IPR004001
PANTHER PTHR11937
Pfam PF00022
PRINTS PR00190
SMART SM00268
PROSITE PS00406
PS00432
PS01132

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0032982

myosin filament

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:F1P476

C

Seeded From UniProt

complete

involved_in

GO:0090131

mesenchyme migration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

P

has_regulation_target:(UniProtKB:E1C3A6)

Seeded From UniProt

complete

part_of

GO:0044297

cell body

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0030027

lamellipodium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

PMID:23533145[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0072562

blood microparticle

PMID:22516433[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:23580065[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001827)

Seeded From UniProt

complete

part_of

GO:0071944

cell periphery

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P63268
ensembl:ENSMUSP00000074658

C

Seeded From UniProt

complete

involved_in

GO:0006936

muscle contraction

Reactome:R-HSA-445355

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-445705
Reactome:R-HSA-445704
Reactome:R-HSA-445700
Reactome:R-HSA-445699

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
  2. Bastos-Amador, P et al. (2012) Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. J Proteomics 75 3574-84 PubMed GONUTS page
  3. Pieragostino, D et al. (2013) Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Mol Biosyst 9 1108-16 PubMed GONUTS page