HUMAN:ACE2

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	ACE2
Protein Name(s)	Angiotensin-converting enzyme 2 ACE-related carboxypeptidase Angiotensin-converting enzyme homolog ACEH Metalloprotease MPROT15 Processed angiotensin-converting enzyme 2
External Links
UniProt	Q9BYF1
EMBL	AF291820 AF241254 AY623811 AB193259 AB193260 AB046569 E39033 GQ262784 AY358714 AY217547 CH471074 BC039902 BC048094 AL110224
CCDS	CCDS14169.1
PIR	T14762
RefSeq	NP_068576.1
UniGene	Hs.178098
PDB	1R42 1R4L 1XJP 2AJF 3D0G 3D0H 3D0I 3KBH 3SCI 3SCJ 3SCK 3SCL
PDBsum	1R42 1R4L 1XJP 2AJF 3D0G 3D0H 3D0I 3KBH 3SCI 3SCJ 3SCK 3SCL
ProteinModelPortal	Q9BYF1
SMR	Q9BYF1
BioGrid	121864
DIP	DIP-44689N
IntAct	Q9BYF1
MINT	MINT-4538816
STRING	9606.ENSP00000252519
BindingDB	Q9BYF1
ChEMBL	CHEMBL2096989
DrugBank	DB00722 DB00691
GuidetoPHARMACOLOGY	1614
MEROPS	M02.006
PhosphoSite	Q9BYF1
DMDM	71658783
PaxDb	Q9BYF1
PRIDE	Q9BYF1
Ensembl	ENST00000252519 ENST00000427411
GeneID	59272
KEGG	hsa:59272
UCSC	uc004cxa.1
CTD	59272
GeneCards	GC0XM015579
HGNC	HGNC:13557
HPA	CAB026174 HPA000288
MIM	300335
neXtProt	NX_Q9BYF1
PharmGKB	PA425
eggNOG	NOG71044
GeneTree	ENSGT00520000055576
HOGENOM	HOG000292210
HOVERGEN	HBG000265
InParanoid	Q9BYF1
KO	K09708
OMA	CNPNNPQ
OrthoDB	EOG76HQ13
PhylomeDB	Q9BYF1
TreeFam	TF312861
BRENDA	3.4.15.1
Reactome	REACT_147707
SABIO-RK	Q9BYF1
ChiTaRS	ACE2
EvolutionaryTrace	Q9BYF1
GeneWiki	Angiotensin-converting_enzyme_2
GenomeRNAi	59272
NextBio	65154
PMAP-CutDB	Q9BYF1
PRO	PR:Q9BYF1
Proteomes	UP000005640
Bgee	Q9BYF1
CleanEx	HS_ACE2
Genevestigator	Q9BYF1
GO	GO:0009986 GO:0005737 GO:0005576 GO:0005615 GO:0070062 GO:0016021 GO:0045121 GO:0005886 GO:0004180 GO:0004175 GO:0001948 GO:0017046 GO:0001618 GO:0008270 GO:0002005 GO:0002003 GO:0003051 GO:0044267 GO:0060135 GO:2000379 GO:0032800 GO:0046813 GO:0042127 GO:0001817 GO:0050727 GO:0003081 GO:0019229 GO:0042312 GO:0009615 GO:0046718
InterPro	IPR001548
PANTHER	PTHR10514
Pfam	PF01401
PRINTS	PR00791
PROSITE	PS00142

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:1903598	positive regulation of gap junction assembly	PMID:12967627^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:Q96KN9)\|has_input:(UniProtKB:P17302)	Seeded From UniProt	complete
involved_in	GO:1903779	regulation of cardiac conduction	PMID:12967627^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:Q96KN9)\|has_input:(UniProtKB:P17302)	Seeded From UniProt	complete
enables	GO:0004180	carboxypeptidase activity	PMID:15283675^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(UniProtKB:P01019:PRO_0000032457)\|has_direct_input:(UniProtKB:P01019:PRO_0000032458)	Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:23533145^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:19056867^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001088)	Seeded From UniProt	complete
involved_in	GO:0051957	positive regulation of amino acid transport	PMID:19185582^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000379	positive regulation of reactive oxygen species metabolic process	PMID:15380922^[6]	ECO:0000305	curator inference used in manual assertion	GO:0004180	P		Seeded From UniProt	complete
involved_in	GO:0050727	regulation of inflammatory response	PMID:15380922^[6]	ECO:0000305	curator inference used in manual assertion	GO:0004180	P		Seeded From UniProt	complete
involved_in	GO:0046813	receptor-mediated virion attachment to host cell	PMID:18343844^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0097746	regulation of blood vessel diameter	PMID:15380922^[6]	ECO:0000305	curator inference used in manual assertion	GO:0004180	P		Seeded From UniProt	complete
involved_in	GO:0032800	receptor biosynthetic process	PMID:18258853^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019229	regulation of vasoconstriction	PMID:15380922^[6]	ECO:0000305	curator inference used in manual assertion	GO:0004180	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:18343844^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:18258853^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0004180	carboxypeptidase activity	PMID:18258853^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004180	carboxypeptidase activity	PMID:15380922^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004180	carboxypeptidase activity	PMID:10924499^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	PMID:18258853^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	PMID:10924499^[9]	ECO:0000305	curator inference used in manual assertion	GO:0004180	P		Seeded From UniProt	complete
involved_in	GO:0003051	angiotensin-mediated drinking behavior	PMID:18258853^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002003	angiotensin maturation	PMID:10924499^[9]	ECO:0000305	curator inference used in manual assertion	GO:0004180	P		Seeded From UniProt	complete
involved_in	GO:0001817	regulation of cytokine production	PMID:15380922^[6]	ECO:0000305	curator inference used in manual assertion	GO:0004180	P		Seeded From UniProt	complete
enables	GO:0001618	virus receptor activity	PMID:18343844^[7]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:24227843^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
NOT\|enables	GO:0008241	peptidyl-dipeptidase activity	PMID:10924499^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
NOT\|enables	GO:0008237	metallopeptidase activity	PMID:10924499^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21068237^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:10969042^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0004180	carboxypeptidase activity	PMID:10969042^[12]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004175	endopeptidase activity	PMID:15283675^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(UniProtKB:P01019)	Seeded From UniProt	complete
enables	GO:0001618	virus receptor activity	PMID:24227843^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0008238	exopeptidase activity	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001630211 UniProtKB:P12821	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1917258 MGI:MGI:87874 PANTHER:PTN001630211 RGD:2493 UniProtKB:P12821 UniProtKB:Q9BYF1	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0012037 FB:FBgn0016122 PANTHER:PTN001630211 RGD:2493 RGD:728890 UniProtKB:F1NYM0 UniProtKB:P12821 UniProtKB:Q9BYF1	C		Seeded From UniProt	complete
enables	GO:0004180	carboxypeptidase activity	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002575178 RGD:728890 UniProtKB:Q9BYF1	F		Seeded From UniProt	complete
involved_in	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002575179 UniProtKB:Q9BYF1	P		Seeded From UniProt	complete
enables	GO:0004181	metallocarboxypeptidase activity	PMID:11815627^[14]	ECO:0000269	experimental evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004181	metallocarboxypeptidase activity	PMID:10969042^[12]	ECO:0000269	experimental evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004181	metallocarboxypeptidase activity	PMID:10924499^[9]	ECO:0000269	experimental evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0060452	positive regulation of cardiac muscle contraction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R0I0 ensembl:ENSMUSP00000107890	P		Seeded From UniProt	complete
part_of	GO:0031526	brush border membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R0I0 ensembl:ENSMUSP00000107890	C		Seeded From UniProt	complete
involved_in	GO:0015827	tryptophan transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R0I0 ensembl:ENSMUSP00000107890	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R0I0 ensembl:ENSMUSP00000107890	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R0I0 ensembl:ENSMUSP00000107890	C		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001548	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001548	C		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:18279660^[15]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0042127	regulation of cell population proliferation	PMID:17703127^[16]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	PMID:10924499^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	PMID:15165741^[17]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-2022379 Reactome:R-HSA-2022378	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0002003	angiotensin maturation	Reactome:R-HSA-2022379 Reactome:R-HSA-2022378	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
enables	GO:0004180	carboxypeptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0121	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
enables	GO:0001618	virus receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1183	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Donoghue, M et al. (2003) Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. J. Mol. Cell. Cardiol. 35 1043-53 PubMed GONUTS page
↑ ^2.0 ^2.1 Rice, GI et al. (2004) Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. Biochem. J. 383 45-51 PubMed GONUTS page
↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
↑ Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page
↑ Camargo, SM et al. (2009) Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations. Gastroenterology 136 872-82 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Huentelman, MJ et al. (2004) Cloning and characterization of a secreted form of angiotensin-converting enzyme 2. Regul. Pept. 122 61-7 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Lin, HX et al. (2008) Identification of residues in the receptor-binding domain (RBD) of the spike protein of human coronavirus NL63 that are critical for the RBD-ACE2 receptor interaction. J. Gen. Virol. 89 1015-24 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Feng, Y et al. (2008) Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation. Circ. Res. 102 729-36 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 ^9.4 ^9.5 ^9.6 Tipnis, SR et al. (2000) A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J. Biol. Chem. 275 33238-43 PubMed GONUTS page
↑ ^10.0 ^10.1 Heurich, A et al. (2014) TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein. J. Virol. 88 1293-307 PubMed GONUTS page
↑ Shulla, A et al. (2011) A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry. J. Virol. 85 873-82 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 Donoghue, M et al. (2000) A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ. Res. 87 E1-9 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 ^13.3 ^13.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Vickers, C et al. (2002) Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J. Biol. Chem. 277 14838-43 PubMed GONUTS page
↑ Lu, Y et al. (2008) Lipid rafts are involved in SARS-CoV entry into Vero E6 cells. Biochem. Biophys. Res. Commun. 369 344-9 PubMed GONUTS page
↑ Raizada, MK & Ferreira, AJ (2007) ACE2: a new target for cardiovascular disease therapeutics. J. Cardiovasc. Pharmacol. 50 112-9 PubMed GONUTS page
↑ Turner, AJ et al. (2004) ACE2: from vasopeptidase to SARS virus receptor. Trends Pharmacol. Sci. 25 291-4 PubMed GONUTS page

[PMID:12967627-1] 1.0 ^1.1 Donoghue, M et al. (2003) Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. J. Mol. Cell. Cardiol. 35 1043-53 PubMed GONUTS page

[PMID:15283675-2] 2.0 ^2.1 Rice, GI et al. (2004) Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. Biochem. J. 383 45-51 PubMed GONUTS page

[PMID:23533145-3] Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page

[PMID:19056867-4] Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page

[PMID:19185582-5] Camargo, SM et al. (2009) Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations. Gastroenterology 136 872-82 PubMed GONUTS page

[PMID:15380922-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Huentelman, MJ et al. (2004) Cloning and characterization of a secreted form of angiotensin-converting enzyme 2. Regul. Pept. 122 61-7 PubMed GONUTS page

[PMID:18343844-7] 7.0 ^7.1 ^7.2 Lin, HX et al. (2008) Identification of residues in the receptor-binding domain (RBD) of the spike protein of human coronavirus NL63 that are critical for the RBD-ACE2 receptor interaction. J. Gen. Virol. 89 1015-24 PubMed GONUTS page

[PMID:18258853-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 Feng, Y et al. (2008) Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation. Circ. Res. 102 729-36 PubMed GONUTS page

[PMID:10924499-9] 9.0 ^9.1 ^9.2 ^9.3 ^9.4 ^9.5 ^9.6 Tipnis, SR et al. (2000) A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J. Biol. Chem. 275 33238-43 PubMed GONUTS page

[PMID:24227843-10] 10.0 ^10.1 Heurich, A et al. (2014) TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein. J. Virol. 88 1293-307 PubMed GONUTS page

[PMID:21068237-11] Shulla, A et al. (2011) A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry. J. Virol. 85 873-82 PubMed GONUTS page

[PMID:10969042-12] 12.0 ^12.1 ^12.2 Donoghue, M et al. (2000) A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ. Res. 87 E1-9 PubMed GONUTS page

[PMID:21873635-13] 13.0 ^13.1 ^13.2 ^13.3 ^13.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11815627-14] Vickers, C et al. (2002) Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J. Biol. Chem. 277 14838-43 PubMed GONUTS page

[PMID:18279660-15] Lu, Y et al. (2008) Lipid rafts are involved in SARS-CoV entry into Vero E6 cells. Biochem. Biophys. Res. Commun. 369 344-9 PubMed GONUTS page

[PMID:17703127-16] Raizada, MK & Ferreira, AJ (2007) ACE2: a new target for cardiovascular disease therapeutics. J. Cardiovasc. Pharmacol. 50 112-9 PubMed GONUTS page

[PMID:15165741-17] Turner, AJ et al. (2004) ACE2: from vasopeptidase to SARS virus receptor. Trends Pharmacol. Sci. 25 291-4 PubMed GONUTS page

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HUMAN:ACE2

Contents

Annotations

Notes

References

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