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HUMAN:A6NCP5
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ARHGAP44 (ECO:0000313 with Ensembl:ENSP00000342566) (synonyms: RICH2 (ECO:0000313 with EMBL:AAI43854.1)) | |
| Protein Name(s) | RICH2 protein (ECO:0000313 with EMBL:AAI43854.1)
Rho GTPase-activating protein 44 (ECO:0000313 with Ensembl:ENSP00000342566) cDNA FLJ58097, moderately similar to Homo sapiens Rho GTPase activating protein 17 (ARHGAP17), transcript variant 1, mRNA (ECO:0000313 with EMBL:BAG57745.1) | |
| External Links | ||
| UniProt | A6NCP5 | |
| EMBL | AC005274 AC005277 BC143853 AK294538 | |
| RefSeq | XP_005256945.1 | |
| UniGene | Hs.499758 | |
| ProteinModelPortal | A6NCP5 | |
| SMR | A6NCP5 | |
| Ensembl | ENST00000340825 | |
| GeneID | 9912 | |
| KEGG | hsa:9912 | |
| UCSC | uc002gns.4 | |
| CTD | 9912 | |
| HGNC | HGNC:29096 | |
| GeneTree | ENSGT00760000118863 | |
| HOGENOM | HOG000179193 | |
| HOVERGEN | HBG000015 | |
| GenomeRNAi | 9912 | |
| NextBio | 35462455 | |
| ExpressionAtlas | A6NCP5 | |
| GO | GO:0005737 GO:0007165 | |
| Gene3D | 1.10.555.10 1.20.1270.60 | |
| InterPro | IPR027267 IPR004148 IPR008936 IPR000198 | |
| Pfam | PF03114 PF00620 | |
| SMART | SM00721 SM00324 | |
| SUPFAM | SSF48350 | |
| PROSITE | PS51021 PS50238 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0098887 |
neurotransmitter receptor transport, endosome to postsynaptic membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2144423 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098886 |
modification of dendritic spine |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2144423 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0061001 |
regulation of dendritic spine morphogenesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2144423 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0048786 |
presynaptic active zone |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000716326 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0048365 |
Rac GTPase binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2144423 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043197 |
dendritic spine |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2144423 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035021 |
negative regulation of Rac protein signal transduction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2144423 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032956 |
regulation of actin cytoskeleton organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2144423 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031256 |
leading edge membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000716326 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000716326 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0038747 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031256 |
leading edge membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005543 |
phospholipid binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0099152 |
regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0099010 |
modification of postsynaptic structure |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098887 |
neurotransmitter receptor transport, endosome to postsynaptic membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098886 |
modification of dendritic spine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0061001 |
regulation of dendritic spine morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0048365 |
Rac GTPase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043197 |
dendritic spine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043087 |
regulation of GTPase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035021 |
negative regulation of Rac protein signal transduction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032956 |
regulation of actin cytoskeleton organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SSM3 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051056 |
regulation of small GTPase mediated signal transduction |
Reactome:R-HSA-194840 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-194922 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0045202 |
synapse |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006887 |
exocytosis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030054 |
cell junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005768 |
endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0055037 |
recycling endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043197 |
dendritic spine |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 Galic, M et al. (2012) External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane. Nat. Cell Biol. 14 874-81 PubMed GONUTS page
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- GO:0048365 ! Rac GTPase binding
- GO:0055037 ! recycling endosome
- GO:0051056 ! regulation of small GTPase mediated signal transduction
- GO:0043087 ! regulation of GTPase activity
- GO:0099152 ! regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane
- GO:0032956 ! regulation of actin cytoskeleton organization
- GO:0061001 ! regulation of dendritic spine morphogenesis
