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HRSVA:NS1
Contents
Species (Taxon ID) | Human respiratory syncytial virus A (strain A2). (11259) | |
Gene Name(s) | 1C (synonyms: NS1) | |
Protein Name(s) | Non-structural protein 1
NS1 Non-structural protein 1C | |
External Links | ||
UniProt | P0DOE9 | |
EMBL | M11486 U50362 U50363 U63644 AF035006 | |
PIR | A94336 | |
SMR | P0DOE9 | |
IntAct | P0DOE9 | |
PRIDE | P04544 | |
Proteomes | UP000007678 UP000134464 UP000181145 UP000181262 UP000181559 | |
GO | GO:0033650 GO:0039545 GO:0039502 | |
InterPro | IPR005099 | |
Pfam | PF03438 | |
ProDom | PD009407 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0039501 |
suppression by virus of host type I interferon production |
ECO:0000314 |
P |
Figure 3 shows by ELISA that wild type cells expressing NS1 inhibit INF-α and INF-β while cells that have had the NS1 gene removed (ΔNS1) express high levels of the INFs. |
complete | |||||
involved_in |
GO:0039501 |
suppression by virus of host type I interferon production |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0033650 |
host cell mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030683 |
evasion or tolerance by virus of host immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039503 |
suppression by virus of host innate immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039502 |
suppression by virus of host type I interferon-mediated signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039545 |
suppression by virus of host MAVS activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0030430 |
host cell cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Spann, KM et al. (2004) Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]. J. Virol. 78 4363-9 PubMed GONUTS page
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