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HORSE:PA21B

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Species (Taxon ID) Equus caballus (Horse). (9796)
Gene Name(s) PLA2G1B
Protein Name(s) Phospholipase A2

Group IB phospholipase A2 Phosphatidylcholine 2-acylhydrolase 1B Phospholipase A2 isoform 2

External Links
UniProt P00594
PIR A90615
ProteinModelPortal P00594
SMR P00594
STRING 9796.ENSECAP00000007194
eggNOG NOG290764
HOGENOM HOG000231749
HOVERGEN HBG008137
InParanoid P00594
Proteomes UP000002281
GO GO:0005576
GO:0005509
GO:0004623
GO:0016042
GO:0006644
Gene3D 1.20.90.10
InterPro IPR001211
IPR013090
IPR016090
PANTHER PTHR11716
Pfam PF00068
PRINTS PR00389
SMART SM00085
SUPFAM SSF48619
PROSITE PS00119
PS00118

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0048146

positive regulation of fibroblast proliferation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000197126
UniProtKB:P00592
UniProtKB:P04054

P

Seeded From UniProt

complete

enables

GO:0047498

calcium-dependent phospholipase A2 activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000919171
RGD:3340
RGD:61949
RGD:62051
RGD:620857
UniProtKB:P04054

F

Seeded From UniProt

complete

involved_in

GO:0006644

phospholipid metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101899
MGI:MGI:1349661
PANTHER:PTN000919171
RGD:61949
RGD:620857
UniProtKB:P14555

P

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000197126
RGD:61949
UniProtKB:P00592
UniProtKB:P04054

P

Seeded From UniProt

complete

enables

GO:0005543

phospholipid binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000919171
UniProtKB:P14555

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000919171
UniProtKB:P04054

F

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101842
PANTHER:PTN000197126
RGD:61949
UniProtKB:P00592
UniProtKB:P04054

F

Seeded From UniProt

complete

enables

GO:0004623

phospholipase A2 activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101842
MGI:MGI:101899
MGI:MGI:1349661
PANTHER:PTN000919171
RGD:61935
RGD:61949
UniProtKB:P00592
UniProtKB:P04054
UniProtKB:P14555

F

Seeded From UniProt

complete

enables

GO:0004623

phospholipase A2 activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001211
InterPro:IPR016090
InterPro:IPR036444

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001211

F

Seeded From UniProt

complete

involved_in

GO:0006644

phospholipid metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016090
InterPro:IPR036444

P

Seeded From UniProt

complete

involved_in

GO:0016042

lipid catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001211

P

Seeded From UniProt

complete

involved_in

GO:0050482

arachidonic acid secretion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016090
InterPro:IPR036444

P

Seeded From UniProt

complete

enables

GO:0004623

phospholipase A2 activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.4

F

Seeded From UniProt

complete

enables

GO:0102567

phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.4

F

Seeded From UniProt

complete

enables

GO:0102568

phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.4

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0016042

lipid catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0442

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page