HORSE:IFNB

Species (Taxon ID)	Equus caballus (Horse). (9796)
Gene Name(s)	IFNB1 (synonyms: IFNB)
Protein Name(s)	Interferon beta IFN-beta
External Links
UniProt	P05012
EMBL	M14546
PIR	G24912
RefSeq	NP_001092910.1
UniGene	Eca.16087
ProteinModelPortal	P05012
SMR	P05012
STRING	9796.ENSECAP00000002382
Ensembl	ENSECAT00000003356
GeneID	100052545
KEGG	ecb:100052545
CTD	3456
eggNOG	NOG43895
GeneTree	ENSGT00760000119150
HOGENOM	HOG000230501
HOVERGEN	HBG052086
InParanoid	P05012
KO	K05415
OMA	NGRLEYC
OrthoDB	EOG7J9VRD
TreeFam	TF336177
Proteomes	UP000002281
GO	GO:0005615 GO:0051607
Gene3D	1.20.1250.10
InterPro	IPR009079 IPR012351 IPR000471 IPR015588
PANTHER	PTHR11691 PTHR11691:SF7
Pfam	PF00143
PRINTS	PR00266
SMART	SM00076
SUPFAM	SSF47266
PROSITE	PS00252

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0043330	response to exogenous dsRNA	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000914537 UniProtKB:P01574	P	Seeded From UniProt	complete
involved_in	GO:0042100	B cell proliferation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107657 PANTHER:PTN000914537	P	Seeded From UniProt	complete
involved_in	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000914537 UniProtKB:P01574	P	Seeded From UniProt	complete
involved_in	GO:0030183	B cell differentiation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2448469 PANTHER:PTN000914537	P	Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2448469 PANTHER:PTN000914537 UniProtKB:Q9P0W0	P	Seeded From UniProt	complete
involved_in	GO:0006959	humoral immune response	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107657 PANTHER:PTN000914537	P	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107657 MGI:MGI:107659 MGI:MGI:107662 MGI:MGI:107664 MGI:MGI:107668 PANTHER:PTN000914537	C	Seeded From UniProt	complete
enables	GO:0005132	type I interferon receptor binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107657 MGI:MGI:2448469 PANTHER:PTN000914537 UniProtKB:Q9P0W0	F	Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107657 MGI:MGI:107668 PANTHER:PTN000914537 UniProtKB:P01574	F	Seeded From UniProt	complete
involved_in	GO:0002323	natural killer cell activation involved in immune response	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107659 MGI:MGI:107664 MGI:MGI:107668 PANTHER:PTN000914537	P	Seeded From UniProt	complete
involved_in	GO:0002286	T cell activation involved in immune response	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107668 PANTHER:PTN000914537	P	Seeded From UniProt	complete
involved_in	GO:0002250	adaptive immune response	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107657 PANTHER:PTN000914537	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005125	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005125	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005125	P	Seeded From UniProt	complete
involved_in	GO:2001235	positive regulation of apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
involved_in	GO:2000552	negative regulation of T-helper 2 cell cytokine production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
involved_in	GO:0060337	type I interferon signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
involved_in	GO:0045581	negative regulation of T cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
involved_in	GO:0045071	negative regulation of viral genome replication	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
involved_in	GO:0043330	response to exogenous dsRNA	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
involved_in	GO:0035458	cellular response to interferon-beta	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
involved_in	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
enables	GO:0008811	chloramphenicol O-acetyltransferase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	F	Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	F	Seeded From UniProt	complete
involved_in	GO:0002312	B cell activation involved in immune response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01574 ensembl:ENSP00000369581	P	Seeded From UniProt	complete
enables	GO:0005126	cytokine receptor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000471	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000471	C	Seeded From UniProt	complete
involved_in	GO:0006952	defense response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000471	P	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0202	C	Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0051	P	Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0202	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

HORSE:IFNB

Contents

Annotations

Notes

References

a

b

c

d

e

h

l

m

n

p

r

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools