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HORSE:EDNRB

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Species (Taxon ID) Equus caballus (Horse). (9796)
Gene Name(s) EDNRB
Protein Name(s) Endothelin B receptor

ET-B ET-BR Endothelin receptor non-selective type

External Links
UniProt O62709
EMBL AF019072
AF038900
RefSeq NP_001075306.1
UniGene Eca.13045
ProteinModelPortal O62709
STRING 9796.ENSECAP00000022427
PRIDE O62709
GeneID 100033875
KEGG ecb:100033875
CTD 1910
eggNOG NOG278704
HOGENOM HOG000272623
HOVERGEN HBG051443
InParanoid O62709
KO K04198
Proteomes UP000002281
GO GO:0016021
GO:0005886
GO:0004962
GO:0048484
GO:0008217
GO:0042310
InterPro IPR000499
IPR001112
IPR000276
IPR017452
Pfam PF00001
PRINTS PR00571
PR00366
PR00237
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

Contributes to

GO:0043473

pigmentation

PMID:9585428[1]

ECO:0000315

P

A specific mutation of EDNRB leads to white coat color in horses.

complete
CACAO 3566

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P24530

C

Seeded From UniProt

complete

enables

GO:0004962

endothelin receptor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P24530

F

Seeded From UniProt

complete

involved_in

GO:0086100

endothelin receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P24530

P

Seeded From UniProt

complete

involved_in

GO:0019722

calcium-mediated signaling

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P24530

P

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276

F

Seeded From UniProt

complete

enables

GO:0004962

endothelin receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000499
InterPro:IPR001112

F

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276
InterPro:IPR000499
InterPro:IPR001112

P

Seeded From UniProt

complete

involved_in

GO:0008217

regulation of blood pressure

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000499
InterPro:IPR001112

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276
InterPro:IPR000499
InterPro:IPR001112
InterPro:IPR017452

C

Seeded From UniProt

complete

involved_in

GO:0042310

vasoconstriction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000499
InterPro:IPR001112

P

Seeded From UniProt

complete

involved_in

GO:0048484

enteric nervous system development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000499
InterPro:IPR001112

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Metallinos, DL et al. (1998) A missense mutation in the endothelin-B receptor gene is associated with Lethal White Foal Syndrome: an equine version of Hirschsprung disease. Mamm. Genome 9 426-31 PubMed GONUTS page