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HHV11:KITH
Contents
Species (Taxon ID) | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1). (10299) | |
Gene Name(s) | TK | |
Protein Name(s) | Thymidine kinase | |
External Links | ||
UniProt | P03176 | |
EMBL | V00470 X14112 | |
PIR | E30084 | |
RefSeq | NP_044624.1 | |
PDB | 1E2H 1E2I 1E2J 1E2K 1E2L 1E2M 1E2N 1E2P 1KI2 1KI3 1KI4 1KI6 1KI7 1KI8 1KIM 1OF1 1P7C 1QHI 1VTK 2KI5 2VTK 3F0T 3RDP 3VTK 4IVP 4IVQ 4IVR 4JBX 4JBY 4OQL 4OQM 4OQN 4OQX | |
PDBsum | 1E2H 1E2I 1E2J 1E2K 1E2L 1E2M 1E2N 1E2P 1KI2 1KI3 1KI4 1KI6 1KI7 1KI8 1KIM 1OF1 1P7C 1QHI 1VTK 2KI5 2VTK 3F0T 3RDP 3VTK 4IVP 4IVQ 4IVR 4JBX 4JBY 4OQL 4OQM 4OQN 4OQX | |
DisProt | DP00419 | |
ProteinModelPortal | P03176 | |
SMR | P03176 | |
BindingDB | P03176 | |
DrugBank | DB00787 DB01004 | |
GeneID | 2703374 | |
BRENDA | 2.7.1.21 | |
SABIO-RK | P03176 | |
EvolutionaryTrace | P03176 | |
Proteomes | UP000009294 | |
GO | GO:0005524 GO:0004797 GO:0071897 GO:0006230 | |
Gene3D | 3.40.50.300 | |
InterPro | IPR001889 IPR027417 | |
Pfam | PF00693 | |
SUPFAM | SSF52540 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0004797 |
thymidine kinase activity |
ECO:0000315 |
F |
Figure 3 |
complete | |||||
involved_in |
GO:0009157 |
deoxyribonucleoside monophosphate biosynthetic process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004797 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009157 |
deoxyribonucleoside monophosphate biosynthetic process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004797 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009157 |
deoxyribonucleoside monophosphate biosynthetic process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004797 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004797 |
thymidine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006230 |
TMP biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004797 |
thymidine kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071897 |
DNA biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335150 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335150 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006230 |
TMP biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335150 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004797 |
thymidine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000335150 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071897 |
DNA biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Barquero, AA et al. (1997) Antiviral activity of meliacine on the replication of a thymidine kinase-deficient mutant of Herpes simplex virus type 1 alone and in combination with acyclovir. Int. J. Antimicrob. Agents 9 49-55 PubMed GONUTS page