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HHV11:KITH

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Species (Taxon ID) Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1). (10299)
Gene Name(s) TK
Protein Name(s) Thymidine kinase
External Links
UniProt P03176
EMBL V00470
X14112
PIR E30084
RefSeq NP_044624.1
PDB 1E2H
1E2I
1E2J
1E2K
1E2L
1E2M
1E2N
1E2P
1KI2
1KI3
1KI4
1KI6
1KI7
1KI8
1KIM
1OF1
1P7C
1QHI
1VTK
2KI5
2VTK
3F0T
3RDP
3VTK
4IVP
4IVQ
4IVR
4JBX
4JBY
4OQL
4OQM
4OQN
4OQX
PDBsum 1E2H
1E2I
1E2J
1E2K
1E2L
1E2M
1E2N
1E2P
1KI2
1KI3
1KI4
1KI6
1KI7
1KI8
1KIM
1OF1
1P7C
1QHI
1VTK
2KI5
2VTK
3F0T
3RDP
3VTK
4IVP
4IVQ
4IVR
4JBX
4JBY
4OQL
4OQM
4OQN
4OQX
DisProt DP00419
ProteinModelPortal P03176
SMR P03176
BindingDB P03176
DrugBank DB00787
DB01004
GeneID 2703374
BRENDA 2.7.1.21
SABIO-RK P03176
EvolutionaryTrace P03176
Proteomes UP000009294
GO GO:0005524
GO:0004797
GO:0071897
GO:0006230
Gene3D 3.40.50.300
InterPro IPR001889
IPR027417
Pfam PF00693
SUPFAM SSF52540

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004797

thymidine kinase activity

PMID:18611819[1]

ECO:0000315

F

Figure 3

complete

involved_in

GO:0009157

deoxyribonucleoside monophosphate biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004797

P

Seeded From UniProt

complete

involved_in

GO:0009157

deoxyribonucleoside monophosphate biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004797

P

Seeded From UniProt

complete

involved_in

GO:0009157

deoxyribonucleoside monophosphate biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004797

P

Seeded From UniProt

complete

enables

GO:0004797

thymidine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001889

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001889

F

Seeded From UniProt

complete

involved_in

GO:0006230

TMP biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001889

P

Seeded From UniProt

complete

enables

GO:0004797

thymidine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.1.21

F

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000335150

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000335150

F

Seeded From UniProt

complete

involved_in

GO:0006230

TMP biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000335150

P

Seeded From UniProt

complete

enables

GO:0004797

thymidine kinase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000335150

F

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0237

P

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Barquero, AA et al. (1997) Antiviral activity of meliacine on the replication of a thymidine kinase-deficient mutant of Herpes simplex virus type 1 alone and in combination with acyclovir. Int. J. Antimicrob. Agents 9 49-55 PubMed GONUTS page