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HHV11:DNBI
Contents
| Species (Taxon ID) | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1). (10299) | |
| Gene Name(s) | DBP (synonyms: ICP8) | |
| Protein Name(s) | Major DNA-binding protein
Infected cell protein 8 ICP-8 protein | |
| External Links | ||
| UniProt | P04296 | |
| EMBL | X14112 X03181 M21631 DQ889502 FJ593289 | |
| PIR | A03790 | |
| RefSeq | NP_044631.1 | |
| PDB | 1URJ | |
| PDBsum | 1URJ | |
| BioGrid | 971471 | |
| IntAct | P04296 | |
| MINT | MINT-191337 | |
| GeneID | 2703458 | |
| EvolutionaryTrace | P04296 | |
| Proteomes | UP000009294 | |
| GO | GO:0042025 GO:0046872 GO:0003697 GO:0006260 | |
| InterPro | IPR000635 | |
| Pfam | PF00747 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0039715 |
nuclear viral factory |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039686 |
bidirectional double-stranded viral DNA replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000281441 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000281441 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000281441 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0039686 |
bidirectional double-stranded viral DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000281441 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000281441 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Darwish, AS et al. (2015) ICP8 Filament Formation Is Essential for Replication Compartment Formation during Herpes Simplex Virus Infection. J. Virol. 90 2561-70 PubMed GONUTS page
- ↑ Leinbach, SS & Heath, LS (1988) A carboxyl-terminal peptide of the DNA-binding protein ICP8 of herpes simplex virus contains a single-stranded DNA-binding site. Virology 166 10-6 PubMed GONUTS page
- ↑ He, X & Lehman, IR (2000) Unwinding of a herpes simplex virus type 1 origin of replication (Ori(S)) by a complex of the viral origin binding protein and the single-stranded DNA binding protein. J. Virol. 74 5726-8 PubMed GONUTS page
- ↑ Quinlan, MP et al. (1984) The intranuclear location of a herpes simplex virus DNA-binding protein is determined by the status of viral DNA replication. Cell 36 857-68 PubMed GONUTS page
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