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HELPY:URE23

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Species (Taxon ID) Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori). (85962)
Gene Name(s) ureA (ECO:0000255 with HAMAP-Rule:MF_01955) (synonyms: hpuA)
Protein Name(s) Urease subunit alpha (ECO:0000255 with HAMAP-Rule:MF_01955)

Urea amidohydrolase subunit alpha (ECO:0000255 with HAMAP-Rule:MF_01955)

External Links
UniProt P14916
EMBL X17079
M60398
AB032429
AE000511
PIR A38537
RefSeq NP_206873.1
WP_000779223.1
YP_006933995.1
PDB 1E9Y
1E9Z
PDBsum 1E9Y
1E9Z
ProteinModelPortal P14916
SMR P14916
DIP DIP-3146N
IntAct P14916
MINT MINT-180633
STRING 85962.HP0073
PRIDE P14916
DNASU 900171
EnsemblBacteria AAD07144
GeneID 13869249
900171
KEGG heo:C694_00355
hpy:HP0073
PATRIC 20591349
KO K14048
OMA ISMEIME
OrthoDB EOG69PQ9G
BioCyc HPY:HP0073-MONOMER
UniPathway UPA00258
EvolutionaryTrace P14916
Proteomes UP000000429
GO GO:0005737
GO:0016151
GO:0009039
GO:0009405
GO:0043419
Gene3D 2.10.150.10
3.30.280.10
HAMAP MF_01954
MF_01955
InterPro IPR002019
IPR008223
IPR002026
Pfam PF00699
PF00547
PIRSF PIRSF001225
ProDom PD002319
SUPFAM SSF51278
SSF54111
TIGRFAMs TIGR00192
TIGR00193

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043419

urea catabolic process

PMID:1313413[1]

ECO:0000315

P

Table 2: The ureA mutant showed no urease activity, which was measured by the rate of release of urea.

complete
CACAO 6323

involved_in

GO:0043419

urea catabolic process

PMID:1313413[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016151

nickel cation binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002026
InterPro:IPR036463

F

Seeded From UniProt

complete

involved_in

GO:0043419

urea catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002026
InterPro:IPR008223
InterPro:IPR036463

P

Seeded From UniProt

complete

enables

GO:0009039

urease activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.1.5

F

Seeded From UniProt

complete

enables

GO:0009039

urease activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087123

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087123

C

Seeded From UniProt

complete

involved_in

GO:0019627

urea metabolic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087123

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0043419

urea catabolic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00258

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Cussac, V et al. (1992) Expression of Helicobacter pylori urease genes in Escherichia coli grown under nitrogen-limiting conditions. J. Bacteriol. 174 2466-73 PubMed GONUTS page