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HELPY:HCPB
Contents
| Species (Taxon ID) | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori). (85962) | |
| Gene Name(s) | hcpB | |
| Protein Name(s) | Beta-lactamase HcpB
Cysteine-rich protein B | |
| External Links | ||
| UniProt | O25103 | |
| EMBL | AE000511 | |
| PIR | H64561 | |
| PDB | 1KLX | |
| PDBsum | 1KLX | |
| ProteinModelPortal | O25103 | |
| SMR | O25103 | |
| DIP | DIP-3342N | |
| IntAct | O25103 | |
| MINT | MINT-160080 | |
| STRING | 85962.HP0336 | |
| PRIDE | O25103 | |
| EnsemblBacteria | AAD07408 | |
| PATRIC | 20591907 | |
| eggNOG | COG0790 | |
| OMA | SIACEAN | |
| OrthoDB | EOG6TJ7WZ | |
| BioCyc | HPY:HP0336-MONOMER | |
| EvolutionaryTrace | O25103 | |
| Proteomes | UP000000429 | |
| GO | GO:0008800 GO:0008152 GO:0046677 | |
| Gene3D | 1.25.40.10 | |
| InterPro | IPR006597 IPR011990 | |
| Pfam | PF08238 | |
| SMART | SM00671 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0008800 |
beta-lactamase activity |
ECO:0000314 |
F |
Table 1: Purified HcpB hydrolyzes several antibiotics by opening of the beta-lactam ring, which was monitored by absorption variation. |
complete | |||||
|
enables |
GO:0008800 |
beta-lactamase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008800 |
beta-lactamase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Luthy, L et al. (2002) The crystal structure of Helicobacter pylori cysteine-rich protein B reveals a novel fold for a penicillin-binding protein. J. Biol. Chem. 277 10187-93 PubMed GONUTS page